Effects of warming carbon dioxide pneumoperitoneum on the prognosis of patients undergoing pancreaticoduodenectomy by Da Vinci robot

Yuan Chen, Jiefang Shen, Qianjian Qian, Wang Wei, Gong Rujie
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Abstract

Objective To study the effect of heated carbon dioxide pneumoperitoneum on the prognosis of patients undergoing pancreaticoduodenectomy by Da Vinci robot. Methods A total of 307 patients who underwent pancreaticoduodenectomy by Da Vinci robot from January 2016 to December 2018 were selected as subjects. 140 patients who underwent pancreaticoduodenectomy from January 2016 to April 2017 were selected as the control group, and room temperature carbon dioxide pneumoperitoneum was used. From May 2017 to December 2018, 167 patients were set as the intervention group, and heated carbon dioxide pneumoperitoneum was used. Body temperature, heart rate and blood oxygen saturation of the two groups were compared after entering the operating room, before anesthesia, before the establishment of carbon dioxide pneumoperitoneum and after the closure of carbon dioxide pneumoperitoneum, and the duration of operation, intraoperative blood loss, postoperative anesthesia recovery time, hospitalization time and postoperative complication rate were recorded. Results There was no significant difference in body temperature after entering the operating room, before the establishment of carbon dioxide pneumoperitoneum between the two groups (P>0.05). After the closure of carbon dioxide pneumoperitoneum, the decline range of the body temperature of the control group was(1.24±2.36) ℃, which was significantly higher than that of the intervention group (0.60±0.25) ℃, and the difference was statistically significant (t value was 6.892, P 0.05). The intraoperative blood loss, resuscitation time, drainage time was (291.08±265.42) ml, (27.04±10.89) min, (8.69±6.64) d in the intervention group and (364.29±309.28) ml, (32.60±12.17) min, (10.76±6.25) d in the control group, and the difference was statistically significant (t value was 2.232, 7.294, 2.789, P<0.05 or 0.01). There was statistically significant difference in The incidence of pancreatic fistula and biliary fistula, and length of hospital stay was 20 cases, 7 cases, (27.62±17.30) d in the intervention group, and 31 cases, 15 cases, (32.38±12.22) d in the control group, and the difference was statistically significant (χ2 value was 4.653, 4.870, t value was 6.284, P<0.05). Conclusions Warming carbon dioxide pneumoperitoneum can reduce the incidence of perioperative hypothermia and improve the prognosis of patients undergoing pancreaticoduodenectomy by Da Vinci robot. Key words: Warming carbon dioxide pneumoperitoneum; Da Vinci robot; Pancreaticod-uodenectomy; Prognosis; Hypothermia
增温二氧化碳气腹对达芬奇机器人胰十二指肠切除术患者预后的影响
目的探讨二氧化碳加热气腹对达芬奇机器人胰十二指肠切除术患者预后的影响。方法选取2016年1月至2018年12月采用达芬奇机器人行胰十二指肠切除术的307例患者作为研究对象。选取2016年1月至2017年4月行胰十二指肠切除术的患者140例作为对照组,采用室温二氧化碳气腹。选取2017年5月至2018年12月167例患者作为干预组,采用加热二氧化碳气腹。比较两组患者进入手术室后、麻醉前、二氧化碳气腹建立前、二氧化碳气腹关闭后的体温、心率、血氧饱和度,记录手术时间、术中出血量、术后麻醉恢复时间、住院时间及术后并发症发生率。结果两组患者进入手术室后、二氧化碳气腹建立前体温差异无统计学意义(P>0.05)。二氧化碳气腹关闭后,对照组体温下降幅度为(1.24±2.36)℃,显著高于干预组(0.60±0.25)℃,差异有统计学意义(t值为6.892,P < 0.05)。干预组术中出血量、复苏时间、引流时间分别为(291.08±265.42)ml、(27.04±10.89)min、(8.69±6.64)d,对照组为(364.29±309.28)ml、(32.60±12.17)min、(10.76±6.25)d,差异有统计学意义(t值分别为2.232、7.294、2.789,P<0.05或0.01)。干预组胰瘘、胆道瘘发生率、住院时间分别为20例、7例(27.62±17.30)d,对照组31例、15例(32.38±12.22)d,差异有统计学意义(χ2值为4.653、4.870,t值为6.284,P<0.05)。结论升温二氧化碳气腹可降低达芬奇机器人行胰十二指肠切除术患者围手术期低温的发生率,改善预后。关键词:增温二氧化碳气腹;达芬奇机器人;Pancreaticod-uodenectomy;预后;体温过低
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