Sensor/Actuator Elements Based on SAW Principle for Flexible Disposable Laboratories-on-a-Chip for Biomedical Analysis

2019 IEEE Conference of Russian Young Researchers in Electrical and Electronic Engineering (EIConRus) Pub Date : 2019-01-01 DOI:10.1109/EICONRUS.2019.8656999

Vladislav E. Lemozerskii, T. Zimina, N. Sitkov, Alexey S. Koigerov, A. V. Pudova

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引用次数: 2

Abstract

The design and technology of sensor/actuator elements (SAE) based on SAW principle, integrated into hybrid analytical microdevices (laboratories-on-a-chip) have been considered. The sample element was implemented on the lithium niobate crystal 128 ° YX LiNbO3 by using metal deposition and standard lithography approaches. The working frequency range was 10 – 17 MHz. The SAE was integrated with microfluidic system for transport of biological fluids. The topology and frequency/amplitude regimes of the system were optimized in order to increase the precision of manipulation of liquid analytes. The device is tested using model system, containing baking east cells, dyes and blood cells. The selectivity of the model system enabled blood cells to be separated. On this basis the potential performance of the system when used in preparative applications, such as blood separation for infusion, is evaluated as 0.5 ml.min-1. The devise could be used in mobile express biomedical applications.

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基于SAW原理的柔性一次性片上实验室生物医学分析传感器/执行器元件

考虑了基于SAW原理的传感器/执行器元件(SAE)的设计和技术，并将其集成到混合分析微设备(片上实验室)中。采用金属沉积法和标准光刻法在铌酸锂晶体128°YX LiNbO3上实现了样品元件。工作频率范围为10 - 17mhz。该SAE与微流体系统集成，用于生物流体的输送。优化了系统的拓扑结构和频率/振幅机制，以提高液体分析物的操作精度。该装置采用含有烘焙细胞、染料和血细胞的模型系统进行测试。模型系统的选择性使血细胞能够被分离。在此基础上，该系统用于制备应用(如输注血液分离)时的潜在性能评估为0.5 ml.min-1。该装置可用于移动快速生物医学应用。

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来源期刊

2019 IEEE Conference of Russian Young Researchers in Electrical and Electronic Engineering (EIConRus)

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