Postoperative Analgesic Efficacy of Tramadol and Diclofenac Sodium in ‎Goats

S. Buhari, J. Amaje, Z. M. Bello, S. Ahmad, N. Abubakar, H. Bodinga, M. Sani
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Abstract

Postoperative analgesic effects of tramadol and diclofenac in goats presented for diaphyseal femoral fracture management were compared. Eight adult goats aged 10 to 24 months (16±5.2 months) were used. The first group of 4 goats received 3 mg/kg of tramadol intramuscularly (IM), and 2.5 mg/kg of diclofenac sodium was administered to the second group of 4 goats before induction of anesthesia IM. Mechanical pain scores, clinico-physiological and red and white blood cell counts were evaluated over a period of twelve hours post drug administration. The study groups were not revealed to the postoperative pain assessors until the end of the study. There was no significant difference in the rectal temperature values and the analgesiometer readings between the tramadol and diclofenac groups (p<0.05). The variations in the pulse rate, respiratory rate, red and white blood cell counts between the groups fluctuated within the normal physiological limits.It was therefore concluded that preoperative intramuscular administration of tramadol at 3 mg/kg provided similar effective postoperative analgesia with diclofenac at 2.5 mg/kg IM following femoral diaphyseal fracture management in goats.
曲马多与双氯芬酸钠在山羊术后的镇痛效果
比较曲马多和双氯芬酸治疗山羊股骨干骨折的术后镇痛效果。选用10 ~ 24月龄(16±5.2月龄)的成年山羊8只。第一组4只羊在肌内注射曲马多3 mg/kg,第二组4只羊在肌内麻醉前注射双氯芬酸钠2.5 mg/kg。在给药后12小时内评估机械疼痛评分、临床生理和红细胞计数。直到研究结束,研究小组才向术后疼痛评估员透露。曲马多组与双氯芬酸组直肠温度值及镇痛计读数差异无统计学意义(p<0.05)。两组之间脉搏率、呼吸率、红细胞和白细胞计数的变化都在正常的生理范围内波动。由此得出结论,术前肌内给药曲马多3mg /kg与双氯芬酸2.5 mg/kg IM在山羊股骨干骨折治疗后的镇痛效果相似。
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