Features of blood clotting system in girls with abnormal uterine bleeding of the puberty period

Q4 Medicine

Sklifosovsky Journal Emergency Medical Care Pub Date : 2022-01-19 DOI:10.24884/2072-6716-2021-22-4-70-75

A. V. Emelyanova, V. M. Shaytor, M. Revnova, D. I. Shaytor, E. Y. Airapetian

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引用次数: 1

Abstract

Objective: to evaluate the blood clotting system based on laboratory data in adolescent girls with uterine bleeding of the puberty period (MCPP). The study included 151 girls from 9 to 17 years old, of which 101 patients with MСPP and 50 patients with somatic pathology who do not suffer from MСPP. All patients underwent laboratory tests of blood coagulation parameters. The results of the study revealed lower values of the prothrombin index (PTI) and a tendency of compensatory increase in fibrinogen levels with a decrease in Duke bleeding time in the period of acute uterine bleeding in patients of the main group. In patients with MСPP, the threshold values of the blood clotting system parameters for the occurrence of uterine bleeding were determined, these are the level of PTI≤71.25%, fibrinogen ≤4.45 g/l, bleeding time according to Duque <2.38 min (p<0,05 according to the criterion χ2). The analysis of the obtained results indicates the presence of signs of insufficiency of the vascular-platelet hemostasis link in girls with MCPP.

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青春期子宫异常出血女童凝血系统的特点

目的:基于实验室资料评价青春期少女子宫出血(MCPP)的凝血系统。该研究包括151名9至17岁的女孩，其中101名患有MСPP, 50名患有躯体病理的患者没有MСPP。所有患者均接受了血液凝固参数的实验室检查。研究结果显示，主组患者急性子宫出血期间凝血酶原指数(PTI)值较低，纤维蛋白原水平有代偿性升高的趋势，同时Duke出血时间缩短。MСPP患者凝血系统参数发生子宫出血的阈值为PTI水平≤71.25%，纤维蛋白原≤4.45 g/l，出血时间按Duque值<2.38 min (χ2判定标准p< 0.05)。对所得结果的分析表明，在MCPP女孩中存在血管-血小板止血环节不足的迹象。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Sklifosovsky Journal Emergency Medical Care Medicine-Emergency Medicine

CiteScore

0.90

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The Journal "Neotlozhnaia meditsinskaia pomoshch" (parallel titles: Zhurnal im. N.V. Sklifosovskogo "Neotlozhnai︠a︡ medit︠s︡inskai︠a︡ pomoshch", "Sklifosovsky Journal of Emergency Medical Care") seeks to publish original research articles, literature reviews, case reports, brief reports on clinical practice, and other suitable material submitted by professionals involved in the diagnosis and treatment of acute medical and surgical conditions.