Vibrational spectroscopy and its future applications in microbiology

IF 5.4 2区化学 Q1 INSTRUMENTS & INSTRUMENTATION

Applied Spectroscopy Reviews Pub Date : 2021-06-28 DOI:10.1080/05704928.2021.1942894

M. Jansson, Martin Kögler, S. Hörkkö, T. Ala-Kokko, L. Rieppo

{"title":"Vibrational spectroscopy and its future applications in microbiology","authors":"M. Jansson, Martin Kögler, S. Hörkkö, T. Ala-Kokko, L. Rieppo","doi":"10.1080/05704928.2021.1942894","DOIUrl":null,"url":null,"abstract":"Abstract Vibrational spectroscopic techniques, namely Fourier transform infrared (FTIR) and Raman spectroscopy, are based on the study of molecular vibrations, and they are complementary techniques to each other. This review provides an overview of the vibrational spectroscopic techniques applied in microbiology during the past decade. In addition, future applications of the elaborated spectroscopic techniques will be highlighted. The results of this review show that both FTIR and Raman spectroscopy are promising alternatives to conventional diagnostic approaches because they provide label-free and noninvasive bacterial detection, identification, and antibiotic susceptibility testing in a single step. Cost-effective, accurate, and rapid tests are needed in order to improve diagnostics and patient care, to decrease the use of unnecessary antimicrobial agents, to prevent resistant microbials, and to decrease the overall burden of outbreaks. Prior to that, however, the presented approaches need to be validated in a clinical workflow against the conventional diagnostic approaches.","PeriodicalId":8100,"journal":{"name":"Applied Spectroscopy Reviews","volume":null,"pages":null},"PeriodicalIF":5.4000,"publicationDate":"2021-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Spectroscopy Reviews","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1080/05704928.2021.1942894","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INSTRUMENTS & INSTRUMENTATION","Score":null,"Total":0}

引用次数: 4

Abstract

Abstract Vibrational spectroscopic techniques, namely Fourier transform infrared (FTIR) and Raman spectroscopy, are based on the study of molecular vibrations, and they are complementary techniques to each other. This review provides an overview of the vibrational spectroscopic techniques applied in microbiology during the past decade. In addition, future applications of the elaborated spectroscopic techniques will be highlighted. The results of this review show that both FTIR and Raman spectroscopy are promising alternatives to conventional diagnostic approaches because they provide label-free and noninvasive bacterial detection, identification, and antibiotic susceptibility testing in a single step. Cost-effective, accurate, and rapid tests are needed in order to improve diagnostics and patient care, to decrease the use of unnecessary antimicrobial agents, to prevent resistant microbials, and to decrease the overall burden of outbreaks. Prior to that, however, the presented approaches need to be validated in a clinical workflow against the conventional diagnostic approaches.

查看原文本刊更多论文

振动光谱学及其在微生物学中的应用前景

振动光谱技术，即傅里叶变换红外(FTIR)和拉曼光谱技术，是基于分子振动的研究，它们是相互补充的技术。本文综述了近十年来振动光谱技术在微生物学研究中的应用。此外，还将重点介绍详细的光谱技术的未来应用。这篇综述的结果表明，FTIR和拉曼光谱都是传统诊断方法的有希望的替代方法，因为它们提供了无标签和无创的细菌检测、鉴定和抗生素敏感性测试。为了改进诊断和患者护理，减少不必要的抗微生物药物的使用，预防耐药微生物，并减轻疫情的总体负担，需要具有成本效益、准确和快速的检测。然而，在此之前，所提出的方法需要在临床工作流程中与传统诊断方法进行验证。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Applied Spectroscopy Reviews 工程技术-光谱学

CiteScore

13.80

自引率

1.60%

发文量

审稿时长

1 months

期刊介绍： Applied Spectroscopy Reviews provides the latest information on the principles, methods, and applications of all the diverse branches of spectroscopy, from X-ray, infrared, Raman, atomic absorption, and ESR to microwave, mass, NQR, NMR, and ICP. This international, single-source journal presents discussions that relate physical concepts to chemical applications for chemists, physicists, and other scientists using spectroscopic techniques.