Results of laparoscopic choledocholithoextraction and choledochoscopy for difficult choledocholithiasis: a single centre experience

Y. Susak, M. Maksimenko, L. Markulan, R. Honza, I. I. Tiuliukin, V. V. Volkovetskii
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Abstract

The management of difficult choledocholithiasis, which accounts for 10—15% of all cases of bile duct stones, has not yet been definitively defined. One of the treatment options for difficult choledocholithiasis is laparoscopic choledocholithoextraction combined with choledochoscopy. Objective — to evaluate the experience of a single centre in the treatment of difficult choledocholithiasis using laparoscopic choledocholithoextraction and choledochoscopy. Materials and methods. A total of 47 patients, including 16 (34%) men and 31 (66%) women with difficult choledocholithiasis, were enrolled in the study and received treatment at our centre. All patients were operated on using laparoscopic choledocholithoextraction combined with choledochoscopy. Thereafter, the results of treatment were analysed for the cohort of patients. In the study, we identified the causes of difficult choledocholithiasis and evaluated the achievement of complete bile duct clearance, the surgery duration, total and postoperative bed days, complications, and mortality. Results. All patients underwent laparoscopic choledocholithoextraction combined with choledochoscopy. The causes of difficult choledocholithiasis were as follows: characteristics of bile duct stones — 27 (57.4%), altered anatomy of the organs of the hepatopancreatobiliary zone — 11 (23.6%), specific location of bile duct stones — 9 (19.1%). After laparoscopic choledocholitoextraction combined with choledochoscopy, complete bile duct clearance was achieved in 95.7% of cases. The average duration of the operation was 130.0±14.7 min. The length of hospital stay after surgery was, on average, 14.3±1.7 days. 4 (8.5%) patients had complications corresponding to classes II (2 (4.2%)) and III (2 (4.2%)) according to the standardized Clavien‑Dindo classification (2009). Conclusions. Laparoscopic choledocholithoextraction combined with choledochoscopy can be used as one of the technologies for the treatment of difficult choledocholithiasis.  
腹腔镜胆总管取出和胆道镜治疗难治性胆总管结石的结果:单中心经验
难治性胆总管结石占所有胆管结石病例的10-15%,其治疗尚未得到明确定义。难治性胆总管结石的治疗选择之一是腹腔镜胆总管取出术联合胆总管镜检查。目的:评价单中心应用腹腔镜取石和胆道镜治疗难治性胆总管结石的经验。材料和方法。共有47例难治性胆总管结石患者入组研究,其中男性16例(34%),女性31例(66%),并在本中心接受治疗。所有患者均行腹腔镜胆总管取石联合胆道镜手术。随后,对该队列患者的治疗结果进行分析。在这项研究中,我们确定了难治性胆总管结石的原因,并评估了胆管完全清除的成就、手术时间、总和术后住院天数、并发症和死亡率。结果。所有患者均行腹腔镜胆总管取石联合胆道镜检查。难治性胆总管结石的原因有:胆管结石特点27例(57.4%),肝胰胆管区脏器解剖改变11例(23.6%),胆管结石部位特殊9例(19.1%)。经腹腔镜胆总管取出联合胆道镜检查后,95.7%的病例胆管完全通畅。手术时间平均130.0±14.7 min,术后住院时间平均14.3±1.7 d。根据标准化Clavien - Dindo分类(2009),有4例(8.5%)患者出现II级(2例(4.2%))和III级(2例(4.2%))并发症。结论。腹腔镜胆总管取出术联合胆道镜检查可作为治疗难治性胆总管结石的技术之一。
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