C1 Esterase Inhibitor (Human) for the Treatment of Acute Hereditary Angioedema

IF 3 Q2 Medicine
S. Valle, A. T. França, R. Campos, A. Grumach
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引用次数: 1

Abstract

Hereditary angioedema (HAE) is a relatively rare disease characterized by acute episodes of swelling. These swellings can be disfiguring, painful and life-threatening. Since the symptoms occur in different areas and most patients experience a delay in their diagnosis, resulting in unnecessary suffering and dangerous situations. HAE can have a tremendous impact on the quality of life. The major genetic deficiency in this disorder is either an absent or nonfunctional C1INH which regulates the complement, fibrinolitic, kalikrein and plasmin pathways.
C1酯酶抑制剂(人)治疗急性遗传性血管性水肿
遗传性血管性水肿(HAE)是一种相对罕见的疾病,其特征是急性发作性肿胀。这些肿胀可能会毁容、疼痛并危及生命。由于症状出现在不同的部位,而且大多数患者的诊断出现延误,导致不必要的痛苦和危险情况。HAE可对生活质量产生巨大影响。这种疾病的主要遗传缺陷是缺乏或无功能的C1INH,它调节补体、纤溶蛋白、钾化酶和纤溶蛋白途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.70
自引率
0.00%
发文量
0
审稿时长
8 weeks
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