M. Osipenko, Aleksandr P. Nadeev, Yuliya Yu. Venzhina, Elena A. Zhuk
{"title":"Clinical case of Whipple’s disease","authors":"M. Osipenko, Aleksandr P. Nadeev, Yuliya Yu. Venzhina, Elena A. Zhuk","doi":"10.17816/mechnikov105632","DOIUrl":null,"url":null,"abstract":"The article presents a clinical case of 68-years old patient with a Whipples disease. The diagnosis was made after 10 years of following-up in presence of gastroenterological symptoms. On examination flattened rounded villi with the content of PAS-positive (PAS periodic acid Schiff) foamy macrophages, highly specific for Whipples disease, have been described in the biopsy specimen of the distal duodenum. The therapy led to a distinct positive dynamics persisting for 1 year.","PeriodicalId":12949,"journal":{"name":"HERALD of North-Western State Medical University named after I.I. Mechnikov","volume":"16 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"HERALD of North-Western State Medical University named after I.I. Mechnikov","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17816/mechnikov105632","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The article presents a clinical case of 68-years old patient with a Whipples disease. The diagnosis was made after 10 years of following-up in presence of gastroenterological symptoms. On examination flattened rounded villi with the content of PAS-positive (PAS periodic acid Schiff) foamy macrophages, highly specific for Whipples disease, have been described in the biopsy specimen of the distal duodenum. The therapy led to a distinct positive dynamics persisting for 1 year.