Giant cell reparative granuloma in the temporal bone.

Abstract

A giant cell reparative granuloma (GCRG) occurred in the temporal bone of a 36-year-old woman. Symptoms of hearing loss cleared completely following radiation therapy. From our review of the literature, we judge this to be the first reported case of GCRG in the temporal bone. Also from our review, it appears that GCRG in the temporal bone is usually mistaken for a giant cell tumor. Diagnosis of GCRG in the reviewed material is based on typical histologic pictures as well as clinical information, particularly the fact that patients had a benign final outcome. Giant cell reparative granuloma is a nonneoplastic, benign reactive process caused by trauma and hemorrhage. It responds well to surgical removal. Radiation therapy is the treatment of choice for lesions not amenable to surgery.