Kampo medicine in modern cardiology “1st International Symposium on Kampo Medicine”

T. Ishigami, Hidenori Ito, Y. Nakada, Kazushi Uneda
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Abstract

To the editor, In the field of modern medicine, the requirements and necessity of evidence-based medicine (EBM) are increasingly demanded. Cardiovascular medicine in Japan is no exception. To answer various clinical questions, we need to perform carefully planned clinical trials at a huge expense of various medical resources. These trials are providing statistically validated medical procedures including medical devices and usage medicines for clinical guidelines. To the contrary, various procedures provided by Kampo Medicine are not sufficiently validated by EBM. Traditionally, orally described clinical chips, called “Kuketsu”, for individual subjects are used and applied to treat and cure the patients. Such individual approaches are the strength and characteristics of Kampo treatments in modern medicine, including in cardiology. In the current symposium, we are going to share our experiences of the effectiveness and utility of Kampo medicine in subjects with cardiovascular symptoms and discuss potential applications of Kampo medicine in geriatric cardiology. In the conclusions, we suggest that effective modernization of Kampo medicine in cardiology will be promising to create future integrated medicine with sophisticated combinations of both Kampo and western medicine. The first presentation is “Nutritional Solution Aided by Kampo Medicine in Cardiology.” Currently, malnutrition, frailty, and sarcopenia are becoming major clinical concerns for elderly patients in Japan. In cardiology, these ultimately result in a severe, life-threatening condition, “cardiac cachexia,” which is poorly understood and has no effective medical solutions. Not only physically unhealthy conditions, but also psycho-sociological insufficiencies are causing these health problems that are characteristic for the elderly. Both medical and nursing burdens are growing and ruin social, medical, and individual resources which in Japan are called “Year 2025 Problems,” inducing the medical reconstruction of the community. In this symposium, we are going to propose solutions for geriatric cardiology aided by Kampo medicine in Japan. These might include rehabilitation and multidisciplinary collaboration, both aided by Kampo medicine. In Kampo medicine senescence is seen as the gradual processes of imperceptibly losing vitality, which is called congenital “Qi” in ICD-11, accompanied by impairment of digestive function, which is called “Hi-I-kyo” and is a major source of acquired “Qi” in humans [1]. In Kampo medicine, we have various solutions for treating these conditions such as rikkunshito, hochyuekkito, ninjinyoeito, and so on [2]. These solutions should be beneficial in cardiac malnutrition and might be used in modern medical procedures to settle unresolved conditions such as malnutrition, frailty, sarcopenia and ultimately cardiac cachexia aided by Kampo medicine. The second presentation is “Practice in Cardiology by Kampo Medicine in Japan.” According to the Japanese Society of Hypertension’s Guidelines for the Management of Hypertension, 43 million people in Japan are estimated to be hypertensive [3], edging it toward being endemic. According to the Japanese registry of all cardiac and vascular diseases, in 2012, approximately 210,000 patients presented with heart failure and about 260,000 people developed the disease in 2016, indicating an increase by approximately 10,000 people per year since 2012 [4]. In an aging society the progression of cardiovascular diseases is further accelerated. Western medicine is the main form of treatment of cardiovascular diseases because abundant evidence exists that supports its effectivity, and Kampo medicine is uncommon in clinical practice. However, some formulations of Kampo medicine seem effective in certain cases in which the standard treatments of western medicine fail to obtain satisfactory results, such as cardiac neurosis. It is reported that 90% of medical doctors in Japan have experience with prescribing Kampo medicines, indicating that Kampo medicine plays an important role in modern medicine in Japan. Therefore, it is essential to obtain evidence on Kampo medicines prescribed in medical practice for cardiovascular diseases. In this symposium, I will introduce some case reports of patients with cardiovascular diseases to help understand the construction of evidence. The third presentation is “Kampo Medicine, Ameliorating Patients’ Symptoms, Outperform Routine Cardiology Practices.” Symptoms related to or localized to the chest often cause us anxiety. As we all know, they should be thoroughly diagnosed and treated first by western medicine Received: 20 May 2022 Revised: 21 July 2022 Accepted: 27 July 2022
现代心脏病学中的汉布医学“第一届汉布医学国际研讨会”
在现代医学领域,对循证医学(EBM)的要求和必要性越来越高。日本的心血管医学也不例外。为了回答各种临床问题,我们需要在各种医疗资源的巨大代价下进行精心策划的临床试验。这些试验为临床指南提供了经过统计验证的医疗程序,包括医疗设备和使用药物。相反,Kampo医学提供的各种程序没有得到EBM的充分验证。传统上,口头描述的临床芯片,称为“Kuketsu”,用于个体受试者,并用于治疗和治愈患者。这种个性化的方法是现代医学,包括心脏病学中汉布疗法的优势和特点。在本次研讨会上,我们将分享我们在心血管症状患者中使用汉布药物的有效性和实用性的经验,并讨论汉布药物在老年心脏病学中的潜在应用。在结论中,我们建议在心脏病学中有效地实现汉布医学的现代化,将有希望创造未来的汉布和西医结合的综合医学。第一个报告是“在心脏病学中由汉布医学辅助的营养液”。目前,营养不良、虚弱和肌肉减少症正在成为日本老年患者的主要临床问题。在心脏病学中,这些最终会导致一种严重的、危及生命的疾病,即“心脏恶病质”,人们对这种疾病知之甚少,也没有有效的医学解决方案。造成这些老年人特有的健康问题的原因不仅是身体上的不健康状况,而且还有心理和社会方面的不足。医疗和护理负担都在增加,破坏了社会、医疗和个人资源,这在日本被称为“2025年问题”,引发了社区医疗重建。在这次研讨会上,我们将在日本汉布医学的帮助下提出老年心脏病的解决方案。这些可能包括康复和多学科合作,这两者都得到了汉布医学的帮助。在汉布医学中,衰老被看作是在不知不觉中失去活力的渐进过程,在ICD-11中被称为先天性“气”,伴随着消化功能的损害,被称为“Hi-I-kyo”,是人类获得性“气”的主要来源[1]。在汉布医学中,我们有各种各样的方法来治疗这些疾病,比如“立术”、“合术”、“忍术”等等[2]。这些解决方案应该对心脏营养不良有益,并可能在现代医疗程序中使用,以解决诸如营养不良、虚弱、肌肉减少和最终心脏恶病质等未解决的问题。第二个演讲是"日本汉布医学在心脏病学上的实践"根据日本高血压学会高血压管理指南,日本估计有4300万人患有高血压[3],高血压正逐渐成为地方性疾病。根据日本所有心脏和血管疾病登记处的数据,2012年约有21万名患者出现心力衰竭,2016年约有26万人患上心力衰竭,自2012年以来每年约增加1万人[4]。在老龄化社会中,心血管疾病的发展进一步加快。西医是治疗心血管疾病的主要形式,因为有大量证据支持其有效性,而汉布医学在临床实践中并不常见。然而,在某些西医标准治疗无法取得满意效果的情况下,例如心脏神经症,一些汉方药物的配方似乎有效。据报道,日本90%的医生都有开过汉方药的经验,这表明汉方药在日本现代医学中占有重要地位。因此,在心血管疾病的医疗实践中获得有关汉布药的证据是至关重要的。在这次研讨会上,我将介绍一些心血管疾病患者的病例报告,以帮助理解证据的构建。第三个报告是“汉布医学,改善患者症状,优于常规心脏病学实践。”与胸部有关或局限于胸部的症状常常使我们感到焦虑。众所周知,应该先用西医彻底诊断和治疗。收稿日期:2022年5月20日修订日期:2022年7月21日接受日期:2022年7月27日
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