Celgene Pays US$100 M for Option to Buy Acetylon and Partners with Array BioPharma

Heather Cartwright
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Abstract

Celgene has agreed to pay Acetylon Pharmaceuticals US$100 M upfront in order to obtain an exclusive option to buy the company at a future date for at least US$500 M and potentially more than US$1.6 B. Acetylon will use the non-dilutive funding to advance its portfolio of selective HDAC (histone deacetylase) inhibitors, including its Phase I/II candidate ACY-1215 (rocilinostat) for multiple myeloma. Celgene has also formed a global R&D collaboration with Array BioPharma focused on a preclinical development programme targeting a novel inflammation pathway.
Celgene支付1亿美元购买Acetylon的选择权,并与Array BioPharma合作
Celgene已同意向Acetylon Pharmaceuticals预付1亿美元,以获得在未来以至少5亿美元(可能超过16亿美元)的价格收购该公司的独家选择权。Acetylon将利用这笔非稀释性资金推进其选择性HDAC(组蛋白去乙酰化酶)抑制剂的投资组合,包括用于多发性骨髓瘤的I/II期候选药物ACY-1215 (rocilinostat)。Celgene还与Array BioPharma建立了全球研发合作关系,专注于针对新型炎症途径的临床前开发项目。
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