Fibrin Glue in Temporal Clear Corneal Tunnel Incision

Burkhard Dick, Thomas Kohnen, Volker Hessemer
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引用次数: 2

Abstract

OBJECTIVE: While 3.5 mm clear corneal incisions for the implantation of foldable silicone lenses are commonly accepted, longer incisions for PMMA-IOL implantation are associated with a possibly higher risk of infection and less self-sealing properties. DESIGN: It was intended to reinforce the 5 mm clear corneal tunnel incision after phacoemulsification and IOL-implantation with fibrin adhesive. SETTING: Department of Ophthalmology, University of Giessen, Germany. METHODS: Upon simultaneous mixing of fibrinogen complex and thrombin, the final stages of the coagulation cascade are mimicked after application of fibrin glue, resulting in formation of a fibrin clot. MAIN OUTCOME: The sealant consolidated and adhered to the site of corneal application. The present case demonstrated that fibrin glue is efficacious in watertight wound closure of 5 mm clear corneal incision and provides good support for corneal healing. Only minimal surgically-induced with-the-rule astigmatism was observed. CONCLUSION: In the future, this technique of corneal wound closure might develop as an alternative to singlesuture wound closure after small incision cataract extraction.

纤维蛋白胶在颞透明角膜隧道切口中的应用
目的:虽然3.5 mm透明角膜切口用于可折叠硅胶晶体植入术是普遍接受的,但较长的切口用于PMMA-IOL植入术可能具有较高的感染风险和较差的自密封性。设计:用纤维蛋白粘接剂加固超声乳化人工晶状体植入术后5 mm透明角膜隧道切口。单位:德国吉森大学眼科。方法:同时混合纤维蛋白原复合物和凝血酶,在应用纤维蛋白胶后模拟凝血级联的最后阶段,导致纤维蛋白凝块的形成。主要结果:密封胶在角膜应用部位得到巩固和粘附。本病例证明纤维蛋白胶在5mm透明角膜切口的水密缝合中效果良好,为角膜愈合提供了良好的支撑。仅观察到最小的手术诱导的带尺散光。结论:在未来,这种角膜创面闭合技术可能成为小切口白内障摘除术后单缝合线创面闭合的替代方法。
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