Deranged Pulmonary Function Tests in Allergic Rhinitis in North Indian Patients

S. Monga, J. Malik, A. Sharma, S. Jan, N. Nabi, S. Bahadur
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引用次数: 1

Abstract

Introduction: Significant associations between allergic rhinitis and bronchial asthma have been established and as a result of bronchial hyper-responsiveness, patients can have deranged pulmonary function tests. We aim to compare previous such studies with the result of our study done in India wherein we identify among allergic rhinitis patients who despite not having overt asthmatic symptoms, have pulmonary function derangements, quite possibly at a subclinical disease level. Materials and Methods: We studied 74 patients of allergic rhinitis and after meticulous clinical work up, they underwent blood tests including hemogram, absolute eosinophil count, and total serum IgE followed by pulmonary function tests. Results: Out of 74 patients 60 (81%) had intermittent allergic rhinitis whereas only 14 (19%) had persistent allergic rhinitis. Pulmonary function tests showed reversible obstruction, ie, >10% improvement in FEV1 with inhaled bronchodilators (as seen in asthma) in 18 (24.3%), mild obstruction in 14, and moderate obstruction in 4 cases. Conclusion: The study emphasizes the importance of pulmonary symptoms and the performance of pulmonary function tests in cases of allergic rhinitis patients to rule out latent asthma.
北印度变应性鼻炎患者肺功能紊乱试验
简介:变应性鼻炎和支气管哮喘之间的显著关联已经确立,并且由于支气管高反应性,患者的肺功能检查可能紊乱。我们的目的是将之前的研究与我们在印度进行的研究结果进行比较,我们在过敏性鼻炎患者中发现,尽管没有明显的哮喘症状,但肺功能紊乱,很可能处于亚临床疾病水平。材料与方法:对74例变应性鼻炎患者进行了细致的临床工作,对患者进行血象、嗜酸性粒细胞绝对计数、血清总IgE等血液检查,并进行肺功能检查。结果:74例患者中有60例(81%)患有间歇性变应性鼻炎,而只有14例(19%)患有持续性变应性鼻炎。肺功能检查显示可逆性梗阻,即18例(24.3%)吸入支气管扩张剂(哮喘)使FEV1改善10%,14例为轻度梗阻,4例为中度梗阻。结论:本研究强调了变应性鼻炎患者肺部症状及肺功能检查表现对排除潜在哮喘的重要性。
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