{"title":"Canagliflozin: SGLT2 inhibitor for treating type 2 diabetes","authors":"Richard Donnelly PhD, MD, FRCP, FRACP","doi":"10.1002/fps.101","DOIUrl":null,"url":null,"abstract":"<p>Canagliflozin is a sodium-glucose transporter protein inhibitor under development for the treatment of type 2 diabetes mellitus; it reduces circulatory glucose by facilitating its urinary excretion. In this Drug profile, Richard Donnelly discusses the need for drugs with a mode of action independent of insulin and considers the efficacy and tolerability of canagliflozin in clinical trials, to date, as well as its potential place in management. Copyright © 2013 John Wiley & Sons, Ltd.</p>","PeriodicalId":100566,"journal":{"name":"Future Prescriber","volume":"14 1","pages":"5-7"},"PeriodicalIF":0.0000,"publicationDate":"2013-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/fps.101","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future Prescriber","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/fps.101","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Canagliflozin is a sodium-glucose transporter protein inhibitor under development for the treatment of type 2 diabetes mellitus; it reduces circulatory glucose by facilitating its urinary excretion. In this Drug profile, Richard Donnelly discusses the need for drugs with a mode of action independent of insulin and considers the efficacy and tolerability of canagliflozin in clinical trials, to date, as well as its potential place in management. Copyright © 2013 John Wiley & Sons, Ltd.
卡格列净:用于治疗2型糖尿病的SGLT2抑制剂
Canagliflozin是一种正在开发用于治疗2型糖尿病的钠-葡萄糖转运蛋白抑制剂;它通过促进尿液排泄来减少循环中的葡萄糖。在这篇药物简介中，Richard Donnelly讨论了对具有独立于胰岛素的作用模式的药物的需求，并考虑了迄今为止临床试验中canagliflozin的疗效和耐受性，以及它在治疗中的潜在地位。版权所有©2013 John Wiley &儿子,有限公司
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