No Association Between Lipid Profiles and Acne Vulgaris

K. Nasution, I. Putra, N. Jusuf
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引用次数: 5

Abstract

Background: Acne vulgaris is a chronic inflammation of pilosebaceous follicle that can spontaneously heal with clinical manifestations such as blackhead, papules, pustules, nodule, and cyst on the face, upper chest, arms, and back. Until now, the effect of lipid metabolism on sebaceous gland secretions in the pathogenesis of acne vulgaris is still under research.Materials and Methods: An analytic observational study with cross sectional design involving 30 acne vulgaris and 30 control subjects was conducted. Blood samples were taken from subjects and lipid profile levels were measured. The data were then statistically analyzed.Results: From this research, there was no significant association between lipid profiles with acne vulgaris. There was not any significant difference between the acne vulgaris and the control subjects for total cholesterol, High Density Lipoprotein (HDL), Low Density Lipoprotein (LDL) and triglyceride levels (p>0.05).Conclusion: There is no significant association between lipid profiles levels and acne vulgaris.Keywords: acne vulgaris, lipid profiles, total cholesterol, HDL, LDL, triglyceride
脂质谱与寻常痤疮无关联
背景:寻常痤疮是一种可自愈的毛囊皮脂腺慢性炎症,临床表现为面部、上胸、手臂、背部出现黑头、丘疹、脓疱、结节、囊肿等。到目前为止,脂质代谢对皮脂腺分泌在寻常痤疮发病机制中的作用仍在研究中。材料与方法:采用横断面设计对30例寻常痤疮患者和30例对照组进行分析观察研究。研究人员采集了受试者的血液样本,并测量了血脂水平。然后对数据进行统计分析。结果:从本研究来看,脂质谱与寻常性痤疮之间没有显著的关联。痤疮组总胆固醇、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)和甘油三酯水平与对照组比较,差异均无统计学意义(p>0.05)。结论:脂质水平与寻常性痤疮无显著相关性。关键词:寻常痤疮,脂质谱,总胆固醇,HDL, LDL,甘油三酯
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