THE EFFECTIVENESS OF USING TOOTHPASTE CONTAINING ROBUSTA COFFEE BEAN EXTRACT IN INHIBITING THE FORMATION OF DENTAL PLAQUE

Rina Nanda Prasasti, D. Sari, P. Pujiastuti
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Abstract

Background: Periodontal disease is caused by the interaction between pathogenic bacteria and plaque, without the accumulation of plaque, periodontal disease will not appear. Plaque will be visible one to two days if no oral cleaning steps are taken. The combination of antimicrobial therapy such as antibiotics and mouthwash as well as mechanical therapy such as scaling and root plain gives more effective results. However, if done in the long term it will cause resistance. To overcome this, alternative materials are needed that are used to inhibit bacterial growth, one of which is robusta coffee beans. The content of robusta coffee bean extract contains phenolic and flavonoid compounds that function as antibacterials that work by disrupting the function of the cytoplasmic and cytoplasmic membranes of bacteria. Method: In this study, 6 groups were used, namely KN, K-, K+, KP 25%, KP 50%, and KP 75%. The gingivitis model was made with wire using ligation technique for 3 days, then toothpaste was applied, brushing process, and disclosing agent was given, and the plaque index calculation was PHP (Personal Hygiene Performance). The data obtained were then analyzed using the Kruskall-Wallis test followed by the Mann-Whitney test. Result: The Robusta coffee bean extract toothpaste group at a concentration of 75% experienced a significant reduction in plaque compared to the negative control group and the 25% treatment group (p<0.05), but there were no significant differences or had the same ability when compared to the experimental group. 50% treatment group, normal control group and positive control group. Conclusion: The 75% concentration of Robusta coffee bean extract found in toothpaste is proven to be effective in inhibiting the formation of dental plaque.
使用含有罗布斯塔咖啡豆提取物的牙膏抑制牙菌斑形成的有效性
背景:牙周病是由病原菌与菌斑相互作用引起的,没有菌斑的积累,就不会出现牙周病。如果没有采取清洁口腔的步骤,牙菌斑会在一到两天内出现。抗生素和漱口水等抗菌素治疗以及洗牙和牙根平等机械治疗相结合,效果更佳。然而,如果长期这样做,就会引起阻力。为了克服这个问题,需要替代材料来抑制细菌的生长,其中一种是罗布斯塔咖啡豆。罗布斯塔咖啡豆提取物的内容含有酚类和类黄酮化合物,它们通过破坏细菌的细胞质和细胞质膜的功能而起抗菌作用。方法:本研究采用KN、K-、K+、KP 25%、KP 50%、KP 75% 6组。采用结扎法用铁丝制作牙龈炎模型3 d,然后涂牙膏,进行刷牙过程,给予揭露剂,菌斑指数计算为PHP (Personal Hygiene Performance)。然后使用Kruskall-Wallis测试和Mann-Whitney测试对获得的数据进行分析。结果:75%浓度的罗布斯塔咖啡豆提取物牙膏组与阴性对照组和25%处理组相比,斑块明显减少(p<0.05),但与实验组相比差异不显著或相同。50%治疗组、正常对照组、阳性对照组。结论:在牙膏中发现75%浓度的罗布斯塔咖啡豆提取物被证明对抑制牙菌斑的形成是有效的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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