Empfehlungen zur Prophylaxe der Nebenwirkungen bei intravasaler Applikation jodhaltiger Kontrastmittel

Michael A. Kuefner, Marc Heinrich, Werner Bautz, Michael Uder
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引用次数: 4

Abstract

Iodinated contrast media are widely used in computed tomography and angiography. Adverse reactions such as contrast-medium induced nephropathy (CIN), anaphylactoid reactions and iodine-induced thyrotoxicosis are associated with intravasal administration of contrast agents. Iodinated contrast agents are generately considered to be safe, but in rare cases they can cause severe life threatening situations.

In this review we present an overview about the incidence, pathways, and risk factors of adverse reactions. Simple schemes including hydration protocols for prevention of CIN, medication for prophylaxis of iodine-induced thyrotoxicosis with thyreostatics and anaphylactoid reactions with histamine antagonists and corticosteroids are suggested.

关于在静脉注射时预防副作用的建议
碘造影剂广泛应用于计算机断层扫描和血管造影。造影剂引起的肾病(CIN)、类过敏反应和碘引起的甲状腺毒症等不良反应与静脉内给药造影剂有关。碘造影剂通常被认为是安全的,但在极少数情况下,它们会导致严重的危及生命的情况。在这篇综述中,我们概述了不良反应的发生率、途径和危险因素。建议的简单方案包括预防CIN的水合治疗方案,用甲状腺抑制药物预防碘诱导的甲状腺毒症,以及用组胺拮抗剂和皮质类固醇进行类过敏反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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