Why the Impact of COVID-19 Infection on Babies has, to Date, been Far Milder?

Abstract

The current level of knowledge about the COVID-19 infection on babies and children is still uncertain. Regardless of the world health situation reports especially in developing countries, it remains crucial to maintain a future progress in understanding why babies are less infected than adults. This question is complex and quite speculative. Researchers should include the level of exposure to a confirmed case at which transmission is more likely to occur, taking into consideration the age factor and the immune system, since babies are not very affected by the virus. Sometimes, COVID-19 infection in babies is less commonly reported or absent. This review provides a proposed hypothesis focused on understanding COVID-19 infection on babies. General concepts of vaccination and CoV19 recombination are also outlined.