{"title":"Kinetic modeling and simulation of the gluco regulatory system to detect endocrine system failure","authors":"K.K. Anilkumar , S. Palani","doi":"10.1016/j.rbmret.2005.11.002","DOIUrl":null,"url":null,"abstract":"<div><p>In this paper a mathematical model for blood glucose regulation is developed using compartmental techniques and simulated in windows programming using OWL. The modeling and simulation of the endocrine control system gives the following results: (a) liver failures, (b) pancreas failure and (c) kidney failure. It also helps in the diagnosis of diseases like juvenile diabetes, hypoglycemia and hyperglycemia. It is also programmed to deliver insulin level to the blood upon hyperglycemia. The simulated results are found to justify the pathological behavior.</p></div>","PeriodicalId":100733,"journal":{"name":"ITBM-RBM","volume":"27 2","pages":"Pages 74-79"},"PeriodicalIF":0.0000,"publicationDate":"2006-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbmret.2005.11.002","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ITBM-RBM","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1297956206000076","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
In this paper a mathematical model for blood glucose regulation is developed using compartmental techniques and simulated in windows programming using OWL. The modeling and simulation of the endocrine control system gives the following results: (a) liver failures, (b) pancreas failure and (c) kidney failure. It also helps in the diagnosis of diseases like juvenile diabetes, hypoglycemia and hyperglycemia. It is also programmed to deliver insulin level to the blood upon hyperglycemia. The simulated results are found to justify the pathological behavior.