{"title":"COVID-19 outcomes among people with HIV and COVID-19 in New York City.","authors":"S. Braunstein, Amanda Wahnich, Rachael Lazar","doi":"10.2139/ssrn.4016534","DOIUrl":null,"url":null,"abstract":"BACKGROUND\nLiterature on the impact of HIV on COVID-19-related outcomes remains mixed. Few studies have evaluated COVID-19 outcomes by HIV status using population-based data.\n\n\nMETHODS\nUsing data from New York City (NYC)'s COVID-19 surveillance and HIV surveillance systems prior to the widespread availability of COVID-19 vaccines, we conducted a retrospective cohort study comparing the risk of COVID-19 hospitalization and mortality by HIV status among SARS-CoV-2 diagnoses from February 29-October 17, 2020.\n\n\nRESULTS\nRisk of hospitalization and death among people with HIV (PWH) with COVID-19 were both nearly 30% higher compared with non-PWH. In crude models, incidence of adverse COVID-19 outcomes among PWH compared to non-PWH was elevated in certain groups, including women, Black people, Hispanic/Latino people, Native American people, and multiracial people. CD4 cell count at SARS-CoV-2 diagnosis and presence of an underlying, non-HIV-related condition were independently and strongly associated with risk for COVID-19 hospitalization and death among PWH.\n\n\nCONCLUSION\nNew Yorkers with HIV experienced elevated risk for poor COVID-19 outcomes compared to those without HIV during 2020. PWH, particularly those with low CD4 counts or underlying conditions, should be an ongoing focus for COVID-19 vaccination and rigorous identification and treatment of SARS-CoV-2 infections to prevent adverse outcomes.","PeriodicalId":22572,"journal":{"name":"The Indonesian Journal of Infectious Diseases","volume":"75 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Indonesian Journal of Infectious Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2139/ssrn.4016534","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
BACKGROUND
Literature on the impact of HIV on COVID-19-related outcomes remains mixed. Few studies have evaluated COVID-19 outcomes by HIV status using population-based data.
METHODS
Using data from New York City (NYC)'s COVID-19 surveillance and HIV surveillance systems prior to the widespread availability of COVID-19 vaccines, we conducted a retrospective cohort study comparing the risk of COVID-19 hospitalization and mortality by HIV status among SARS-CoV-2 diagnoses from February 29-October 17, 2020.
RESULTS
Risk of hospitalization and death among people with HIV (PWH) with COVID-19 were both nearly 30% higher compared with non-PWH. In crude models, incidence of adverse COVID-19 outcomes among PWH compared to non-PWH was elevated in certain groups, including women, Black people, Hispanic/Latino people, Native American people, and multiracial people. CD4 cell count at SARS-CoV-2 diagnosis and presence of an underlying, non-HIV-related condition were independently and strongly associated with risk for COVID-19 hospitalization and death among PWH.
CONCLUSION
New Yorkers with HIV experienced elevated risk for poor COVID-19 outcomes compared to those without HIV during 2020. PWH, particularly those with low CD4 counts or underlying conditions, should be an ongoing focus for COVID-19 vaccination and rigorous identification and treatment of SARS-CoV-2 infections to prevent adverse outcomes.