A Review on Effects of Bisphenol a on Reproductive, Endocrine Systems and its Influencing Mechanism

Q4 Biochemistry, Genetics and Molecular Biology

American Journal of Biochemistry and Biotechnology Pub Date : 2021-04-01 DOI:10.3844/ajbbsp.2021.408.422

Ganghui Ye, Liting Zheng, C. Meng, Yuefeng Dong, Hongyan Xu, Qinglu Wang

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Abstract

Corresponding Author: Qinglu Wang College of Sports and Health, Shandong Sport University, China Email: Wql_zcq@126.com Abstract: Background and purpose: Bisphenol A (BPA) is a pervasive environmental toxicant with known adverse effects on human immune system and nervous system et al. Although, BPA is widely known to affect endocrine function in animals, the linkage between human exposure to BPA and human reproductive function is still not clearly clarified. Results: Systematic review of all articles about BPA and human reproductive function identified in SCOPUS and PubMed. Literature was summarized in narrative form and results are presented per category. Some observational surveys investigating the relationship between BPA exposure and human reproductive and/or endocrine function are inconsistent. Conclusion: Our review integrates the studies of BPA on reproductive and/or endocrine system in recent years, mainly explains the effects of BPA on these systems and provides the basis for subsequent studies on BPA.

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双酚A对生殖、内分泌系统的影响及其影响机制研究进展

摘要:背景与目的:双酚A (BPA)是一种普遍存在的环境毒物，已知对人体免疫系统和神经系统等有不良影响。虽然人们普遍知道BPA会影响动物的内分泌功能，但人体暴露于BPA与人体生殖功能之间的联系仍不清楚。结果:系统回顾了SCOPUS和PubMed中所有关于BPA和人类生殖功能的文章。文献以叙述的形式进行总结，并按类别给出结果。一些调查BPA暴露与人类生殖和/或内分泌功能之间关系的观察性调查结果并不一致。结论:本文综述了近年来双酚a对生殖和/或内分泌系统的研究，主要阐述了双酚a对这些系统的影响，为后续双酚a的研究提供了基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Biochemistry and Biotechnology Biochemistry, Genetics and Molecular Biology-Biotechnology

CiteScore

0.70

自引率

0.00%

发文量

期刊介绍： :: General biochemistry :: Patho-biochemistry :: Evolutionary biotechnology :: Structural biology :: Molecular and cellular biology :: Molecular medicine :: Cancer research :: Virology :: Immunology :: Plant molecular biology and biochemistry :: Experimental methodologies