Methodological principles for improving the professional training of doctors in the process of studying biological and bioorganic chemistry in the aspect of chemical safety

A. Ishchenko, Haiova Liudmyla, Oksana Horkunenko
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Abstract

Chemical safety is a component of general and professional competencies of future doctors, namely: general culture (handling of chemical substances, household chemicals); promotion of a healthy lifestyle; prevention of diseases of the population; protection and preservation of public health; providing emergency medical care in emergencies (related to chemical accidents). The article substantiates the method of improving the professional training of future doctors by integrating modern aspects of chemical safety into biochemical training. The potential of the discipline "Biological and Bioorganic Chemistry" as a tool for the formation of competence in chemical safety of future physicians, due to a combination of theoretical training (training material on the mechanisms of inhibition of enzymatic reactions by toxicants; inhibitors and disintegrants of oxidative phosphorylation; molecular mechanisms of action of toxicants; formation and disposal of endogenous toxins; biotransformation of xenobiotics) and laboratory workshops (handling of chemical reagents; modern approaches to hazard labeling and labeling of chemicals; toxicants’ action modeling) is substantiated. The method of studying the educational material of the discipline "Biological and Bioorganic Chemistry" in the context of modern ideas on chemical safety is described. It provides a comprehensive application of modern teaching methods (design, solving situational problems, laboratory experiments, simulating the action of hazardous chemicals, testing) and teaching aids (glossary of terms on biochemical aspects of chemical safety; video lectures and methodical recommendations for independent work of students). The stages of the study method realization of the "Biological and bioorganic chemistry" discipline’s educational material in the context of modern ideas on chemical safety are described. These are the substances’ handling culture formation; formation of biochemical aspects of chemical safety; integration of modern ideas in the field of chemical safety and biochemical components
从化学安全的角度出发,探讨了在生物和生物有机化学研究过程中,加强医师专业培训的方法学原则
化学品安全是未来医生一般和专业能力的一个组成部分,即:一般文化(处理化学物质,家用化学品);提倡健康的生活方式;预防人口疾病;保护和维护公众健康;在紧急情况下提供紧急医疗护理(与化学品事故有关)。本文论述了将现代化工安全知识融入生化培训中,提高未来医师专业培训水平的方法。“生物和生物有机化学”这门学科的潜力是未来医生在化学安全方面形成能力的工具,因为它结合了理论培训(毒物抑制酶促反应机制的培训材料;氧化磷酸化抑制剂和分解剂;毒物作用的分子机制;内源性毒素的形成和处置;异种生物转化)和实验室车间(化学试剂的处理;危险标识和化学品标识的现代方法毒物的作用模型)得到证实。阐述了在现代化学安全思想背景下,研究《生物与生物有机化学》学科教材的方法。它提供了现代教学方法的综合应用(设计,解决情境问题,实验室实验,模拟危险化学品的作用,测试)和教学辅助工具(化学安全的生化方面的术语表;视频讲座和学生独立作业的系统建议)。阐述了现代化学安全思想背景下“生物与生物有机化学”学科教材学习方法实现的阶段。这些是物质的处理文化形成;形成生化方面的化学品安全;在化学安全和生化成分领域整合现代理念
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