{"title":"Recent Advances in the Psychopharmacology of Major Depressive Disorder.","authors":"Laith Alexander, Allan H Young","doi":"10.1192/bja.2022.14","DOIUrl":null,"url":null,"abstract":"<p><p>This review highlights some of the recent advances in the psychopharmacology of Major Depressive Disorder (MDD). We synthesise evidence on emerging pharmacological therapies targeting the serotonergic system, before exploring several novel treatment targets: the glutamatergic system, the GABAergic system, and inflammation. When describing new treatment avenues, we examine the evidence base and how far these new treatments are from routine practice.</p>","PeriodicalId":9336,"journal":{"name":"BJPsych Advances","volume":"58 1","pages":"117-130"},"PeriodicalIF":1.7000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7617086/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BJPsych Advances","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1192/bja.2022.14","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/4/4 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0
Abstract
This review highlights some of the recent advances in the psychopharmacology of Major Depressive Disorder (MDD). We synthesise evidence on emerging pharmacological therapies targeting the serotonergic system, before exploring several novel treatment targets: the glutamatergic system, the GABAergic system, and inflammation. When describing new treatment avenues, we examine the evidence base and how far these new treatments are from routine practice.
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