{"title":"Aminoglycoside Resistance Pattern in Staphylococcus aureusat Hyderabad, Pakistan","authors":"A. A. Patoli, B. Patoli, S. Jabeen, A. Memon","doi":"10.26692/surj/2019.12.94","DOIUrl":null,"url":null,"abstract":"A total of 118 Staphylococcusaureus isolates from various clinical and non-clinical sources were processed for the determination of antibiotic resistance against a set of aminoglycoside group of antibiotics. In this study,44% (n=52) isolates were from various clinical specimens i.e. pus, blood and nose, while 56% (n=66) were recovered from the skin surfaces of healthy volunteers representing the non-clinical isolates. The highest percentage of resistance among both clinical and non-clinical isolates was observed against Neomycin (i.e. clinical = 86.5%, non-clinical = 39.3%). The lowest percentage of resistance among both clinical and non-clinical isolates was observed against Gentamycin (i.e. clinical = 34.6%, non-clinical = 4.5%). The percentage of difference for Amikacin, Gentamycin and To bramycin resistance between clinical non-clinical isolates was observed to be more than 100. The Odd Ratio for Amikacin, Gentamycin and Tobramycin resistance between clinical and non-clinical isolates was 17.75, 11.12, and 20.59, respectively while the p-values were determined as 0.0001 in all the three cases, suggesting a significant association of Amikacin, Gentamycin and Tobramycin resistance with clinical S.aureusisolates.","PeriodicalId":21859,"journal":{"name":"Sindh University Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sindh University Research Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26692/surj/2019.12.94","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A total of 118 Staphylococcusaureus isolates from various clinical and non-clinical sources were processed for the determination of antibiotic resistance against a set of aminoglycoside group of antibiotics. In this study,44% (n=52) isolates were from various clinical specimens i.e. pus, blood and nose, while 56% (n=66) were recovered from the skin surfaces of healthy volunteers representing the non-clinical isolates. The highest percentage of resistance among both clinical and non-clinical isolates was observed against Neomycin (i.e. clinical = 86.5%, non-clinical = 39.3%). The lowest percentage of resistance among both clinical and non-clinical isolates was observed against Gentamycin (i.e. clinical = 34.6%, non-clinical = 4.5%). The percentage of difference for Amikacin, Gentamycin and To bramycin resistance between clinical non-clinical isolates was observed to be more than 100. The Odd Ratio for Amikacin, Gentamycin and Tobramycin resistance between clinical and non-clinical isolates was 17.75, 11.12, and 20.59, respectively while the p-values were determined as 0.0001 in all the three cases, suggesting a significant association of Amikacin, Gentamycin and Tobramycin resistance with clinical S.aureusisolates.