Assessment of serum uric acid level in patients with systemic arterial hypertension

Abstract

Objectives: To study the association between elevated serum uric acid and systemic arterial hypertension. Methods: This study is a case-control study conducted in Al-Sadr Teaching City / Al-Najaf city from December 2019 till the end of February 2020, and included (69) cases diagnosed with systemic arterial hypertension and (71) non- hypertensive. All participants underwent anthropometric measurements and laboratory investigations for serum uric acid level, total cholesterol, high-density lipoprotein level, triglyceride level, serum blood urea and serum creatinine. Results: The study enrolled a total of (140) participants whose mean age was (47.21 ± 12.53) years. Males comprised (57.14%) of total study sample. Serum uric acid level was found to be significantly higher among hypertensive compared to non-hypertensive, P-value = 0.003. Hyperuricemia was found to be significantly correlated with hypertension, with P-value of 0.017, Odds ratio = 9.18 (95% C.I.: 1.12 – 75.50). Conclusions: Serum uric acid level is significantly higher in hypertensive group compared to non-hypertensive group, with the presence of significant numbers with hyperuricemia among hypertensive patients.