Características y evolución de los pacientes con parada cardiorrespiratoria extrahospitalaria sometidos a hipotermia terapéutica

Angélica Bohórquez López , Luis Martín-Villén , Juan J. Egea-Guerrero , Rafael Martín Bermudez , Rafael Hinojosa Pérez , Ángel Herruzo Avilés , Angel Vilches-Arenas
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Abstract

Introduction

Cardiac arrest have secondary co-morbidities, especially neurological outcome. Due to this cirumstances is mandatory to optimized postcardiac arrest management. The objective of this research is to analyze patient's characteristics and outcome after out-hospital cardiac arrest in patients that have undergone therapeutic hypothermia.

Matherial and methods

We conducted a prospective observational study during a two-year period. We included resuscitated patients over eighteen years old who were admitted in to our intensive care unit. These patients had undergone prolonged resuscitation measures and were included in an implemented post-resuscitation protocol which included therapeutic hypothermia.

Results

Thirty-three patients were analyzed. The median time of cardiopulmonary resuscitation was 31.6 minutes. We observed hypoxic/anoxic encephalopathy in 32.3% of cases. This prognosis was associated in those who smoked (p = .04) and with longer time of cardiac arrest (p = .049). Also, the 66.7% of the patients showed a higher incidence of hypoperfusion (p = .049).

Conclusion

In our series hypothermia could be a useful tool in post-resucitation cardiac arrest managment. We also found that the neurological prognosis was associated to non-modifiable risk factors.

治疗性低体温患者院外心肺骤停的特点和演变
心脏骤停有继发性合并症,尤其是神经系统疾病。由于这种情况,必须优化心脏骤停后的处理。本研究的目的是分析院外心脏骤停患者在接受治疗性低温治疗后的特点和结果。材料和方法我们进行了一项为期两年的前瞻性观察研究。我们纳入了18岁以上的复苏病人,他们住进了我们的重症监护室。这些患者接受了长时间的复苏措施,并被纳入实施的复苏后方案,其中包括治疗性低温。结果共分析33例患者。心肺复苏的中位时间为31.6分钟。我们在32.3%的病例中观察到缺氧/缺氧性脑病。这种预后与吸烟(p = 0.04)和心脏骤停时间较长(p = 0.049)相关。66.7%的患者出现低灌注的发生率较高(p = 0.049)。结论在本系列研究中,低温治疗可作为心脏骤停复苏后治疗的有效手段。我们还发现神经预后与不可改变的危险因素有关。
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