Correlation of Serum Parathyroid Hormone and Calcium Level among Pre- and Post-menopausal Women

Journal of Current and Advance Medical Research Pub Date : 2022-05-19 DOI:10.3329/jcamr.v9i1.59739

Sadia Israt Zaman, H. Tabassum, Asma Khan, Umme Shaila

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Abstract

Background: Postmenopausal women are prone to osteoporosis due to estrogen deficiency. Objective: The purpose of the present study was to assess the correlation between serum parathyroid hormone level and serum calcium level among pre- and post-menopausal women. Methodology: This cross-sectional study was conducted in the Department of Physiology at Dhaka Medical College, Dhaka, Bangladesh during the period of January 2012 to December 2012. Women were selected from different areas of Dhaka city. Among them, postmenopausal women with age ranging from 50 to 60 years were taken as group A and apparently healthy premenopausal women with age ranging from 20 to 30 years were included as group B for comparison. Serum calcium and parathyroid hormone levels were estimated to assess the hormonal status in both groups. Results: A total number of seventy (70) postmenopausal women with age ranging from 50 to 60 years and duration of menopause was more than one year. Thirty (30) apparently healthy premenopausal women with age ranging from 20 to 30 years with regular menstrual cycle. Correlation between parathyroid hormone with serum calcium was analyzed. In group A, serum parathyroid hormone showed negative correlation with serum Calcium (r= -0.161, p= 0.184) which was statistically non-significant relationship. In group B, serum parathyroid showed positive correlation with serum calcium (r=+0.232, p=0.218) which was statistically non-significant relationship. Conclusion: In conclusion serum calcium is lower and serum parathyroid hormone is higher in postmenopausal women. Journal of Current and Advance Medical Research, January 2022;9(1):16-20

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绝经前后妇女甲状旁腺激素与钙水平的相关性研究

背景:绝经后妇女由于雌激素缺乏，容易发生骨质疏松症。目的:本研究的目的是评估绝经前和绝经后妇女血清甲状旁腺激素水平和血清钙水平的相关性。方法:本横断面研究于2012年1月至2012年12月期间在孟加拉国达卡达卡医学院生理学系进行。这些妇女是从达卡市的不同地区挑选出来的。其中50 ~ 60岁绝经后妇女为A组，20 ~ 30岁明显健康的绝经前妇女为B组进行比较。测定血清钙和甲状旁腺激素水平以评估两组患者的激素状况。结果:共70例绝经后妇女，年龄50 ~ 60岁，绝经期1年以上。三十(30)名明显健康的绝经前妇女，年龄在20至30岁之间，月经周期正常。分析甲状旁腺激素与血钙的相关性。A组患者血清甲状旁腺激素与血清钙呈负相关(r= -0.161, p= 0.184)，相关性无统计学意义。B组血清甲状旁腺素与血钙呈正相关(r=+0.232, p=0.218)，相关性无统计学意义。结论:绝经后妇女血清钙水平较低，甲状旁腺激素水平较高。现代与先进医学研究杂志，2022;9(1):16-20

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Journal of Current and Advance Medical Research

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