Electrochemical Determination of Dopamine and Uric Acid Using Poly(proline) Modified Carbon Paste Electrode: A Cyclic Voltammetric Study

Abstract

A cyclic voltammetric technique was used for electropolymerisation of proline on the surface of carbon paste electrode and for individual and concurrent determination of dopamine (DA) and uric acid (UA). The surface morphology of the developed electrode was studied by using field emission scanning electron microscopy. The modified electrode showed a high current response towards DA as compared to the bare electrode. The developed modified electrode shows good catalytic activity with a different oxidation potential of DA and UA. The electrode process was found to be adsorption controlled. The developed method shows very good stability and reproducibility. Under the optimized conditions, the concentration range is (1‒2)∙10-4 M and the observed detection limit was 4.7∙10-6 M. The developed sensor was applied for the determination of DA in the real sample with a good recovery.