Progress of radiogenomics in lung cancer

Jianlin Guo, Chuan Zhang, Hualong Yu
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Abstract

Radiogenomics aims at investigating the relationship between radiomics features and genomic features, which has certain practical value in the individualized molecular targeted therapy. Meanwhile, it is noninvasive, repeatable and inexpensive. In recent years, a large number of studies have shown that radiomics features have certain predictive values for the mutation status of driver genes of lung cancer. The application of radiogenomics is insufficient at present, but with its continuous improvement and development, it will play an increasingly important role in the precise therapy of lung cancer in the future. Key words: Lung neoplasms; Receptor, epidermal growth factor; Radiomics; Anaplastic lymphoma kinase
肺癌放射基因组学研究进展
放射基因组学旨在研究放射组学特征与基因组特征之间的关系,在个体化分子靶向治疗中具有一定的实用价值。同时,它是无创的,可重复的和廉价的。近年来,大量研究表明放射组学特征对肺癌驱动基因的突变状态有一定的预测价值。放射基因组学目前的应用尚不充分,但随着其不断完善和发展,未来将在肺癌的精准治疗中发挥越来越重要的作用。关键词:肺肿瘤;受体,表皮生长因子;Radiomics;间变性淋巴瘤激酶
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