Robot-Assisted Versus Laparoscopic Radical Nephrectomy: A Systematic Review and Meta-Analysis

Abstract

Background: For the treatment of renal cell carcinoma, robotic-assisted radical nephrectomy (RARN) has been developed as an alternative to laparoscopic radical nephrectomy (LRN) (RCC). The objective of this systematic review and meta-analysis was to compare the perioperative results of RARN and LRN in the treatment of RCC. Methodology: An exhaustive search of electronic databases from their inception until May 2023 was done. The meta-analysis comprised nine trials with a total of 13,676 individuals who underwent either RARN or LRN. Estimated blood loss, length of hospital stay, conversion rate, transfusion rate, and perioperative complications were evaluated as surgical outcomes. Results: The meta-analysis revealed no statistically significant demographic differences between the two surgical techniques. There were no significant differences between RARN and LRN in terms of predicted blood loss, length of hospital stay, conversion rate, or transfusion rate. The meta-analysis of complications revealed no significant differences between the two surgical methods for intraoperative or postoperative problems. Conclusion: This comprehensive review and meta-analysis suggests that RARN and LRN had comparable perioperative results when used to treat RCC. Although RARN may give prospective benefits in the form of enhanced visibility and dexterity, the clinical significance of these benefits remains unknown. Further high-quality studies with long-term follow-up are required to further comprehend the possible advantages and disadvantages of RARN against LRN in the treatment of RCC. Key words: Robot assisted laparoscopic radical nephrectomy, meta-analysis