Early Implanon Discontinuation and Associated Factors among Woman's of Implanon Users in Ethiopia: A Systematic Review and Meta-Analysis

Ferede Yeshiwas Ayale, Tassew Worku Chekol, Abuhay Teshale Ayanaw
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Abstract

Background: Worldwide, large number of women becomes unprotected to the risk of pregnancy after contraceptive discontinuation. To ensure safe and consistent services addressing the factors that contribute to early Implanon discontinuation is necessary to women in the reproductive age group through appropriate use of contraceptive methods and method switching. Considerable studies have been done in Ethiopia about early implanon discontinuation among implanon users. But inconsistent findings were reported. Thus, this study was conducted to determine the pooled early discontinuation of implanon and to identify associated factors among implanon users in Ethiopia. Methods: Search of Pub Med, Scopus, Web of Science, Google Scholar, MEDLINE, CINAHL, Science Direct and Cochrane Library was conducted to identify relevant studies from November 1, 2022 to November 24, 2022. The Newcastle-Ottawa scale tool was used to measure the quality of included studies. The pooled estimate of early implanon discontinuation was performed using Random effect model. Data extracted independently by two reviewers with a standardized data extraction format and exported to STATA software version11 for meta-analysis. Heterogeneity among studies was checked by Cochrane Q and I2 test statistics. Results: After reviewing 19,002 studies, 8 studies involving 3,022 implanon users were included for this review and meta-analysis. The pooled estimate of early implanon discontinuation among implanon users in Ethiopia was 39.78% (95%CI: 23.03, 56.53). Identified factors associated with early implanon discontinuation were developed side effect (AOR = 1.96; 95%CI: 0.42, 3.35), services dissatisfaction (AOR = 1.27; 95%CI: 0.27, 5.96), having appointment after insertion (AOR = 0.66; 95%CI: 0.23, 1.92), and having pre-insertion counselling (0.75; 95%CI: 0.35, 1.60). Conclusion: The systematic review and meta-analysis of this study revealed that more than three-eighth of implanon user discontinues their implanon early. Experienced side effect, services dissatisfaction, lack of appointment after insertion and inadequate pre-insertion counselling were identified factors associated with early implanon discontinuation among implanon users in Ethiopia. Health care providers should give proper pre insertion counseling based on manual for the clients by giving highlight on side effects. Moreover, improving client service satisfaction and appointment follow-up also should be considered to accelerate the proper use of Implanon.
在埃塞俄比亚妇女的早期植入终止和相关因素的植入用户:系统回顾和荟萃分析
背景:在世界范围内,大量妇女在停止避孕后失去对怀孕风险的保护。为了确保提供安全和一致的服务,育龄妇女必须通过适当使用避孕方法和转换避孕方法,解决导致早期中止计划生育的因素。在埃塞俄比亚,已经对植入物使用者中早期停止植入物进行了大量的研究。但报告的结果却不一致。因此,本研究旨在确定埃塞俄比亚implanon使用者的早期停药情况,并确定相关因素。方法:检索Pub Med、Scopus、Web of Science、Google Scholar、MEDLINE、CINAHL、Science Direct和Cochrane Library,检索时间为2022年11月1日至11月24日的相关研究。纽卡斯尔-渥太华量表工具用于测量纳入研究的质量。采用随机效应模型对早期干扰素停药进行汇总估计。数据由两名审稿人独立提取,采用标准化的数据提取格式,导出到STATA软件版本11进行meta分析。采用Cochrane Q和I2检验统计量检验各研究间的异质性。结果:在回顾了19,002项研究后,本综述和荟萃分析纳入了8项研究,涉及3,022名植入物使用者。埃塞俄比亚干扰素使用者早期停止干扰素的汇总估计为39.78% (95%CI: 23.03, 56.53)。与早期停药相关的因素有:不良反应(AOR = 1.96;95%CI: 0.42, 3.35),服务不满意度(AOR = 1.27;95%CI: 0.27, 5.96),插入后预约(AOR = 0.66;95%CI: 0.23, 1.92),并接受插入前咨询(0.75;95%ci: 0.35, 1.60)。结论:本研究的系统回顾和荟萃分析显示,超过八分之三的植入激素使用者早期停止使用植入激素。经历过的副作用、服务不满意、插入后缺乏预约和插入前咨询不足被确定为与埃塞俄比亚植入用户早期停止植入相关的因素。医疗保健提供者应根据说明书对客户进行适当的插入前咨询,并强调副作用。此外,还应考虑提高客户服务满意度和预约跟踪,以促进Implanon的正确使用。
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