Inhibition and Antimicrobial Activity of Lavandula stoechas Essential Oil on Escherichia coli, Staphylococcus aureus and Candida albicans

Abstract

In the present study, the volatile compounds of essential oil of Lavandula stoechas L. (Lavender) was analysed by gas chromatography-mass spectrometry (GC-MS) using the Nist and Willey libraries. It was determined that the main components of L. stoechas were linalyl acetate (36.31%) and linalool (34.18%). Inhibition and antimicrobial activity of volatile oil of the plant against Escherichia coli (ATCC 25293), Staphylococcus aureus (ATCC25925) and Candida albicans were examined by microbroth dilution method. L. stoechas EO (Essential Oil) exhibited antimicrobial activity with MIC of between 14.8 and 32.5 μg/mL. The lowest antimicrobial activity were determined against E. coli in L. stoechas EO (MIC= 32.5 μg/mL), while maximum MIC were noticed as 14.8 μg/mL against C. albicans. The most cell inhibition were noted as 91.76% in C. albicans at the concentration of 4500 μg/mL of L. stoechas. The reductions in living cell number were obtain as 0.54 log in E. coli, 1.04 log in S. aureus and 1.08 log in C. albicans at the same concentration of 4.5 μg/mL. This study showed the strong antimicrobial performance of L. stoechas EO in detail. This study showed that L. stoechas EO inhibits the growth of microorganisms depending on concentration.