Exploiting semantic structure for mapping user-specified form terms to SNOMED CT concepts

Ritu Khare, Yuan An, Jiexun Li, I. Song, Xiaohua Hu
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引用次数: 9

Abstract

The elements of clinical databases are usually named after the clinical terms used in various design artifacts. These terms are instinctively supplied by the users, and hence, different users often use different terms to describe the same clinical concept. This term diversity makes future database integration and analysis a huge challenge. In this paper, we study the problem of standardization of the terms used in a specific kind of user-designed artifact, the encounter forms or templates, using a popular clinical terminology, the SNOMED CT. In particular, we focus on the problem of mapping the terms on an encounter form to SNOMED CT concepts. Existing term mapping techniques are solely based on syntactic string similarity. Such techniques are unable to disambiguate among the terms that resemble one another linguistically, and yet differ semantically. To improve existing techniques, we consider the context of a term in the mapping process and propose a hybrid approach relying on linguistics as well as structural information. For a given form term, this approach (i) exploits the semantic structure of the form to derive the term's context, and (ii) maps the term to a linguistically- matching SNOMED CT concept that is compatible with the derived context. We test the approach on over 900 clinician-specified terms used in 26 forms. This method achieves 23% improvement in precision and 38% improvement in recall, over a pure linguistic-based approach. Our first contribution is that we introduce and address a new problem of mapping form terms to standard concepts. The second contribution is that the experimental evaluation confirms that structural information has a major role in improving mapping performance, and in addressing the key challenges associated with semantic mapping.
利用语义结构将用户指定的表单术语映射到SNOMED CT概念
临床数据库的元素通常以各种设计工件中使用的临床术语命名。这些术语是由用户本能地提供的,因此,不同的用户经常使用不同的术语来描述相同的临床概念。这种术语的多样性给未来的数据库集成和分析带来了巨大的挑战。在本文中,我们使用流行的临床术语SNOMED CT,研究了特定类型的用户设计工件,遇到表单或模板中使用的术语的标准化问题。特别地,我们关注的问题是将相遇形式上的术语映射到SNOMED CT概念。现有的术语映射技术仅仅基于语法字符串的相似性。这种技术无法消除语言上相似但语义上不同的术语之间的歧义。为了改进现有的技术,我们在映射过程中考虑了术语的上下文,并提出了一种依赖语言学和结构信息的混合方法。对于给定的表单术语,这种方法(i)利用表单的语义结构来派生该术语的上下文,(ii)将该术语映射到与派生上下文兼容的语言匹配的SNOMED CT概念。我们对26种表单中使用的900多个临床指定术语进行了测试。该方法与纯基于语言的方法相比,准确率提高了23%,召回率提高了38%。我们的第一个贡献是引入并解决了将形式术语映射到标准概念的新问题。第二个贡献是实验评估证实了结构信息在提高映射性能和解决与语义映射相关的关键挑战方面具有重要作用。
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