Betterment the production of prodigiosin that was produced from Serratia marcescen by means mutations.

Abstract

Serratia marcescens was exposed to mutation for becoming better the production of prodigiosin (quantitatively and qualitatively) and examined it as antibacterial activities. One isolate of S.marcescen (Wild) was exposed to different kinds of antibiotics (Gentamycin 10μg/ml) to produce mutant isolates from S.marcescen and examined to produce prodigiosin. The isolate that produce the largest amount of prodigiosin among four isolates was used for more studies. Staphyllococcus Baciilus, E.coli, and Pseudomonas were exposed to prodigiosin for testing inhibiting activity of it against these bacterial strains.