Chemical constituents, cytotoxic activities and traditional uses of Micromelum minutum (Rutaceae): a review

Abstract

Rutaceae, the rue family, composed of 160 genera and about 2,070 species of woody shrubs and trees and is distributed in warm temperate and tropical regions.1 The members of Rutaceae family have been used in perfumery, gastronomy, and traditional medicine and several publications have reported the presence of secondary chemical constituents.2 Phytochemical survey of this family reveals alkaloids, coumarins, flavonoids, limonoids, and volatile oils3 and these have been associated to different biological activities, for example, antimicrobial,4 antidiarrhoeal,5 anticholinesterasic,6 antileishmanial,7 antiprotozoal,8 larvicidal,9 and antioxidant activities.10