Emergent Surgical Treatment Results of Inflammatory Bowel Disease and Review of the Literature

C. Goret, N. Goret, O. Ozkan, G. Kiliç
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Abstract

Objective: Inflammatory bowel diseases (IBD) are a group of chronic gastrointestinal system diseases of which the etiology is unknown, and where environmental and genetic factors are influential. Among IBD cases, it has been reported that approximately 1/5 of ulcerative colitis (UC) patients and 4/5 of patients with Crohn’s disease (CD) require surgical intervention. In this study, we retrospectively investigated and presented 14 cases diagnosed as IBD and urgently operated, which are rarely reported in the literature. Material and Method: We retrospectively evaluated who underwent bowel surgery for IBD. A total of 14 who underwent surgical resection of bowel with colectomy or/and segmental small bowel resection due to IBD lesions. Data were collected form Istanbul Ekin Private Pathology Laboratory and Çanakkale State Hospital were enrolled the study. Results: Of the 14 cases that were urgently operated, four (28.6%) were female, ten (71.4%) were male, and the mean age was 45.2. One of the cases (7.1%) was operated due to fistula, three (21.5%) due to perforation and ten (71.4%) due to obstruction. When the histopathological diagnosis of the cases was examined, it was seen that one case (7.1%) was CD+adenocarcinoma, one case (7.1%) was itestinal tuberculosis (tbc), and twelve cases (85.8%) were CD. Conclusion: Based on clinical and histopathological diagnosis, treatment in IBD cases should be regulated according to the localization and severity of the disease and the presence of complications. Surgical treatment should be preferred in IBD cases with inflammation despite medical treatments if remission cannot be achieved, complications such as obstruction/fistula occur, or neoplastic lesions are present.
炎症性肠病的急诊手术治疗结果及文献回顾
目的:炎症性肠病(IBD)是一组病因不明、环境和遗传因素影响的慢性胃肠系统疾病。据报道,在IBD病例中,大约1/5的溃疡性结肠炎(UC)患者和4/5的克罗恩病(CD)患者需要手术治疗。在本研究中,我们回顾性调查并报告了14例诊断为IBD并紧急手术的病例,这些病例在文献中很少报道。材料和方法:我们回顾性评估因IBD接受肠道手术的患者。共有14例患者因IBD病变而行结肠切除术或/和节段性小肠切除术。数据来自伊斯坦布尔Ekin私立病理实验室和Çanakkale国立医院。结果:14例紧急手术患者中,女性4例(28.6%),男性10例(71.4%),平均年龄45.2岁。因瘘1例(7.1%),因穿孔3例(21.5%),因梗阻10例(71.4%)。在检查病例的组织病理学诊断时,发现1例(7.1%)为CD+腺癌,1例(7.1%)为肠结核(tbc), 12例(85.8%)为CD。结论:在临床和组织病理学诊断的基础上,IBD病例应根据疾病的定位、严重程度和并发症的存在来调整治疗。如果不能达到缓解,出现阻塞/瘘管等并发症,或存在肿瘤病变,尽管进行了药物治疗,但仍有炎症的IBD患者应首选手术治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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