Hidden by the hair - a precocious puberty case report

FI Ferreira, S. Costa, C. Pereira, Brígida Robalo, Lurdes Sampaio
{"title":"Hidden by the hair - a precocious puberty case report","authors":"FI Ferreira, S. Costa, C. Pereira, Brígida Robalo, Lurdes Sampaio","doi":"10.25753/BIRTHGROWTHMJ.V29.I1.15113","DOIUrl":null,"url":null,"abstract":"McCune-Albright syndrome (MAS) is one of the conditions causing precocious gonadotropin-independent puberty. It is a rare disease, characterized by two of the three following features: precocious puberty, polyostotic fibrous dysplasia (PFD), and cafe au lait (CAL) skin spots. Herein is presented the case of a girl with pubarche, acne, and transient thelarche since the age of three and menarche since the age of six years old. Besides transitory follicular cysts and advanced bone age, no other changes were found. Diagnosis was only established after brain magnetic resonance imaging showed fibrous dysplasia involving left craniofacial bones. The girl’s parents later mentioned that she had multiple cafe au lait skin spots on the scalp since birth, disclosing how the key diagnostic sign had been covered by the child’s hair. MAS is a rare disorder and diagnosis depends on a high index of suspicion. CAL skin spots are generally the first manifestation, but can easily go unnoticed. Additionally, PFD may only affect some bones, like craniofacial.","PeriodicalId":31313,"journal":{"name":"Nascer e Crescer","volume":"25 1","pages":"126-128"},"PeriodicalIF":0.0000,"publicationDate":"2020-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nascer e Crescer","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25753/BIRTHGROWTHMJ.V29.I1.15113","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

McCune-Albright syndrome (MAS) is one of the conditions causing precocious gonadotropin-independent puberty. It is a rare disease, characterized by two of the three following features: precocious puberty, polyostotic fibrous dysplasia (PFD), and cafe au lait (CAL) skin spots. Herein is presented the case of a girl with pubarche, acne, and transient thelarche since the age of three and menarche since the age of six years old. Besides transitory follicular cysts and advanced bone age, no other changes were found. Diagnosis was only established after brain magnetic resonance imaging showed fibrous dysplasia involving left craniofacial bones. The girl’s parents later mentioned that she had multiple cafe au lait skin spots on the scalp since birth, disclosing how the key diagnostic sign had been covered by the child’s hair. MAS is a rare disorder and diagnosis depends on a high index of suspicion. CAL skin spots are generally the first manifestation, but can easily go unnoticed. Additionally, PFD may only affect some bones, like craniofacial.
隐藏在头发里——一例性早熟病例报告
麦库恩-奥尔布赖特综合征(MAS)是导致性腺激素不依赖性青春期早熟的原因之一。这是一种罕见的疾病,以以下三个特征中的两个为特征:性早熟,多骨纤维发育不良(PFD)和咖啡样皮肤斑点(CAL)。这里提出的情况下,一个女孩与阴部,痤疮和短暂性月经初潮,因为三岁和初潮,因为六岁。除短暂性卵泡囊肿和骨龄提前外,未见其他变化。诊断仅在脑磁共振成像显示纤维性发育不良累及左颅面骨后建立。女孩的父母后来提到,自出生以来,她的头皮上就有多处咖啡色皮肤斑点,并透露了关键的诊断标志是如何被孩子的头发覆盖的。MAS是一种罕见的疾病,诊断依赖于高度的怀疑指数。CAL皮肤斑点通常是第一个表现,但很容易被忽视。此外,PFD可能只影响某些骨骼,如颅面。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
审稿时长
8 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信