The Effects of Obesity and Physical Activity on Dyslipidemia in Persons With Type 2 Diabetes

Yun-A Shin, Jae-Hyun Kim, R. Song, EunSeok Cha
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Abstract

OBJECTIVES This study was conducted to examine the effect of obesity, and physical activity on the prevalence of dyslipidemia in persons with type 2 diabetes mellitus (T2DM).METHODS A cross-sectional , correlational design was used. Participants aged 20 years or older were recruited from a diabetes clinic affiliated with a university hospital. Body composition, blood glucose, glycated hemoglobin, and blood lipid level were measured in addition to self-reported physical activity. Final data analysis was conducted with 177 participants. The differences on physical activity measures and body composition between those with or without dyslipidemia were analyzed using independent t-tests. The associations between dyslipidemia and physical activity and obesity were assessed with the odds Ratio (OR) and 95% confidence intervals (CI) after adjusting potential confounding factors.RESULTS The participation rate of regular physical activity in T2DM patients was 55.9%. BMI and regular physical activity participation influenced the prevalence of dyslipidemia in persons with T2DM. The regular physical activity participation rate of T2DM patients without dyslipidemia was higher than that of T2DM patients with dyslipidemia (p<.05). Moreover, participation in regular physical activity decreased the risk of dyslipidemia prevalence (p<.05). With regard to body composition, T2DM patients with dyslipidemia had a higher body mass index (p<.01). As the body mass index 1 increased, odd ratio of the dyslipidemia prevalence increased 1.21 times (p<.05).CONCLUSIONS The risk of dyslipidemia in T2DM patients was influenced by BMI and participation in regular physical activity. Therefore, reducing obesity through regular physical activity will be a way to lower the prevalence of dyslipidemia in T2DM.
肥胖和体育活动对2型糖尿病患者血脂异常的影响
目的:本研究旨在探讨肥胖和体育活动对2型糖尿病(T2DM)患者血脂异常患病率的影响。方法采用横断面相关设计。年龄在20岁以上的参与者是从大学附属医院的糖尿病诊所招募的。除了自我报告的身体活动外,还测量了身体成分、血糖、糖化血红蛋白和血脂水平。最后对177名参与者进行了数据分析。使用独立t检验分析有或没有血脂异常的人群在体力活动测量和身体组成方面的差异。在调整潜在的混杂因素后,用比值比(OR)和95%置信区间(CI)评估血脂异常与体育活动和肥胖之间的关系。结果T2DM患者定期体育活动参与率为55.9%。BMI和有规律的体育活动参与影响2型糖尿病患者血脂异常的患病率。无血脂异常T2DM患者的常规体力活动参与率高于有血脂异常T2DM患者(p< 0.05)。此外,参加有规律的体育活动降低了血脂异常患病率的风险(p< 0.05)。体成分方面,伴有血脂异常的T2DM患者体质量指数较高(p< 0.01)。随着体重指数1的增加,血脂异常患病率奇比增加1.21倍(p< 0.05)。结论:2型糖尿病患者血脂异常的风险受BMI和参与规律体育活动的影响。因此,通过有规律的体育活动来减少肥胖将是降低2型糖尿病血脂异常患病率的一种方法。
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