{"title":"Nucleotide transfigurations using playback conversion","authors":"B. Kathiresan, G. Karthik","doi":"10.1109/ICCCNT.2013.6726612","DOIUrl":null,"url":null,"abstract":"Bioinformatics is the application of computer technology for the management and analysis of biological data. Pattern matching in a DNA sequence or searching a pattern from a large data base is a major research area in computational biology. One of the major problems in genomic field is to perform pattern comparison on DNA and protein sequences. A full DNA strand contains three billion of nucleotide bases. To parse and to convert amino acids of high volume, the existing approach takes some minutes. If the conversion process is aborted in middle, it will restart from the beginning again. In order to overcome this drawback, the playback conversion approach is proposed to continue the process from where it aborted. And the subsequent implementation of this approach in parallel mode will reduce forty percent of time taken by the existing approach. This paper entirely focuses on an approach to reduce the time taken for the conversion of nucleotide to amino acids. The proposed technique gives very good performance related to DNA sequence analysis for querying of publicly available genome sequence data. These experimental results show that there is considerable increase in the improvement of overall performance.","PeriodicalId":6330,"journal":{"name":"2013 Fourth International Conference on Computing, Communications and Networking Technologies (ICCCNT)","volume":"26 1","pages":"1-5"},"PeriodicalIF":0.0000,"publicationDate":"2013-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2013 Fourth International Conference on Computing, Communications and Networking Technologies (ICCCNT)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICCCNT.2013.6726612","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Bioinformatics is the application of computer technology for the management and analysis of biological data. Pattern matching in a DNA sequence or searching a pattern from a large data base is a major research area in computational biology. One of the major problems in genomic field is to perform pattern comparison on DNA and protein sequences. A full DNA strand contains three billion of nucleotide bases. To parse and to convert amino acids of high volume, the existing approach takes some minutes. If the conversion process is aborted in middle, it will restart from the beginning again. In order to overcome this drawback, the playback conversion approach is proposed to continue the process from where it aborted. And the subsequent implementation of this approach in parallel mode will reduce forty percent of time taken by the existing approach. This paper entirely focuses on an approach to reduce the time taken for the conversion of nucleotide to amino acids. The proposed technique gives very good performance related to DNA sequence analysis for querying of publicly available genome sequence data. These experimental results show that there is considerable increase in the improvement of overall performance.