{"title":"Inhibition of scrapie prion propagation","authors":"Jörg Tatzelt, Konstanze F. Winklhofer","doi":"10.1002/1438-826X(200110)2:2/3<108::AID-GNFD108>3.0.CO;2-S","DOIUrl":null,"url":null,"abstract":"<p>Prion diseases are characterized by the propagation of an abnormally folded protein, denoted scrapie prion protein (PrP<sup>Sc</sup>). Here we review results from our group which reveale different possibilities to interfere with the propagation and accumulation of PrP<sup>Sc</sup> in scrapie-infected cell lines and animal models.</p>","PeriodicalId":100573,"journal":{"name":"Gene Function & Disease","volume":"2 2-3","pages":"108-112"},"PeriodicalIF":0.0000,"publicationDate":"2001-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1438-826X(200110)2:2/3<108::AID-GNFD108>3.0.CO;2-S","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gene Function & Disease","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/1438-826X%28200110%292%3A2/3%3C108%3A%3AAID-GNFD108%3E3.0.CO%3B2-S","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Prion diseases are characterized by the propagation of an abnormally folded protein, denoted scrapie prion protein (PrPSc). Here we review results from our group which reveale different possibilities to interfere with the propagation and accumulation of PrPSc in scrapie-infected cell lines and animal models.
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