Therapeutic Effects of SB 365 Natural Aticancer Drug for Various Cancers with Advanced Stages in 7 Years

Jong-Hwa Lee, Joo-Yeon Gie, Y. Cho, C. Kim, Myung-Seup Chae, E. Kim, Wang-Jae Lee, U-Hyun Park, T. Lau, Josef Sotckenreiter, S. Woehrer, Karl Postbauer
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Abstract

SB is a root extract of plant Pusatilla koreana, used traditionally as an useful antiinflammatory and antitumor agent in South Korea for long times. From March 2013 to December 2019, for 7 years there were 421 consecutive advanced and recurrent various kinds of cancer patients for intensified SB 365 anticancer drug treatment. Two important components, Pulsatilla saponin D is the most effective saponin with cancer cell apoptosis, deoxypodophyllotoxin inhibits new blood vessel formation, and anti-inflammatory effects with immune potentiative activities were confirmed. Cancer studied firstly in pancreas, followed by stomach, large intestine, lung, bile duct, liver, breast, kidney, uterus, oral cavity, esophagus and prostate. Almost of cancers were advanced and recurred status. Intravenous administration was done with intratumoral injection, intraperitoneal or intrathoracic administrations were done with change position, and inhalation therapy was also done. Side effects were clinically insignificant, most commonly fever, chills, nextly injection site pain, erythema, itching, nausea and vomitings were developed. 73.6% of total patients received 1-2 cycles of chemotherapies only, 3 cycles received patient survived for 6 months, 6 cycles survived for 12 months, and 9 cycles or more survived 30 months of survival durations. Pain control with improved appetite and immunity were noted as SB 365 treatments were going on. It is strongly requested to regain the permission of Korean FDA and prompt supports of the national medical insurance, that makes remarkable survival duration and for lesser economic burdons for advanced, recurrent cancer patients and save the funds of national medical insurance. And also highly recommended to make SB treatment available in foreign cancer patients for economic advantages and national image promotions.
sb365天然抗癌药物对各种晚期7年肿瘤的疗效观察
SB是一种植物韩国pusatila koreana的根提取物,在韩国传统上被用作有效的抗炎和抗肿瘤剂。2013年3月至2019年12月,连续7年421例晚期及复发的各类肿瘤患者接受强化SB 365抗癌药物治疗。两种重要成分白头翁皂苷D是抑制癌细胞凋亡最有效的皂苷,脱氧鬼臼毒素抑制新血管形成,具有抗炎作用和免疫增强活性。首先研究的癌症是胰腺,其次是胃、大肠、肺、胆管、肝、乳腺、肾脏、子宫、口腔、食道和前列腺。几乎所有癌症都处于晚期和复发状态。采用瘤内注射方式静脉给药,换体位腹腔或胸腔给药,同时进行吸入治疗。临床不良反应不明显,最常见的是发热、寒战,其次是注射部位疼痛、红斑、瘙痒、恶心和呕吐。73.6%的患者仅接受1-2个化疗周期,3个化疗周期患者存活6个月,6个化疗周期患者存活12个月,9个化疗周期及以上患者存活30个月。随着SB 365治疗的进行,疼痛得到控制,食欲和免疫力得到改善。为了延长晚期和复发癌症患者的生存时间,减轻经济负担,节省国民医疗保险的资金,希望得到食品医药品监督管理局的许可,尽快得到国民医疗保险的支援。同时也强烈建议将SB治疗推广到国外的癌症患者中,以获得经济上的优势和提升国家形象。
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