Link between Two Decades of Oral Contraceptives and Bowel Infarction: A Case Report

Balosin Marina-Georgia
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Abstract

Abstract Objectives: Partial or total necrosis of the bowel is a frequent cause of obstruction of the mesenteric artery or vein. Mesenteric infarction is usually the consequence of other associated pathologies of the patient and most often revealed by acute intestinal obstruction. Thus, it is of utmost importance to recognize the risk factors and treat all conditions that might have a link with a hypercoagulability state. Acute mesenteric ischemia is pathology difficult to treat due to the nonspecific symptomatology and late diagnosis consequently. Moreover, the majority the patients have other comorbidities resulting a mortality in over 50% of the cases. Methods and results: Identified risk factors in our patient’s case for the thrombus formations were oral contraceptive medication, hypertension, and obesity. Other secondary causes of Superior Mesenteric Vein (SMV) and Portal Vein (PV) thrombosis were investigated but all tests were negative leading to the incrimination of obesity and chronic use of oral contraceptives for over two decades. Conclusion: Rare, life-threatening complications of associated pathologies such as venous mesenteric thrombosis and bowel obstruction are unanticipated. Thus, it is of utmost importance to diagnose complications and risk factors as soon as possible whose resolutions will make it possible to prolong survival of many patients. Identification of populations at risk and screening of asymptomatic patients are therefore crucial imperatives.
二十年口服避孕药与肠梗死之间的联系:一例报告
摘要目的:肠部分或全部坏死是肠系膜动脉或静脉梗阻的常见原因。肠系膜梗死通常是患者其他相关病理的结果,最常表现为急性肠梗阻。因此,认识到危险因素并治疗所有可能与高凝状态有关的疾病是至关重要的。急性肠系膜缺血由于症状不特异性和诊断较晚,是病理上难以治疗的疾病。此外,大多数患者有其他合并症,导致50%以上的病例死亡率。方法和结果:本例患者血栓形成的危险因素为口服避孕药、高血压和肥胖。对肠系膜上静脉(SMV)和门静脉(PV)血栓形成的其他继发原因进行了调查,但所有测试均为阴性,导致肥胖和长期使用口服避孕药超过20年。结论:肠系膜静脉血栓形成和肠梗阻等罕见的危及生命的并发症是意料之外的。因此,尽早诊断并发症和危险因素至关重要,其解决将有可能延长许多患者的生存期。因此,确定高危人群和筛查无症状患者至关重要。
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