Effectiveness of High Flow Nasal Oxygen Therapy Vs Non- Invasive Ventilation on Respiratory Parameters among patients with Acute Respiratory Failure

Asian journal of nursing education and research Pub Date : 2023-06-06 DOI:10.52711/2349-2996.2023.00033

J. Gnanarani, K. G, V. K, Nesa Sathya Satchi, Tamilarasi E

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Abstract

Background: Nurses play a critical role in ensuring successful patient outcomes. Preventing cellular damage from hypoxia, preventing acidosis from hypercapnia, and relieving patients' symptoms and distress all require adequate oxygen levels. The goal of oxygen therapy is to supplement the inspired oxygen concentration in order to prevent tissue hypoxia and subsequent cellular dysfunction1. Cellular oxygen delivery is a mechanism that relies on inspired oxygen as well as haemoglobin concentration, its ability to saturate with oxygen, and cardiac output to deliver oxygen to cells (Higgins, 2007)2. Objective: To assess the Effectiveness of High Flow Nasal Oxygen Therapy Vs Non-Invasive Ventilation on Respiratory Parameters among Patients with Acute Respiratory Failure. Methodology: A descriptive research design pretest post-test only design was adopted for the study. Results: The majority of patients with acute respiratory failure treated with HFNC showed ABG parameters such as pH(7.35-7.45), SaO2(94-100%), pO2(80-100mmHg), pCO2(35-45mmHg), and HCO3(22-26mEq/L) on admission, after an hour, 8 hours and 24 hours of admission, were 62.85%, 68.57%, 68.6%, 74.28% and 14%, 57.14%, 51.4%, 47.71% and 62.85%, 68.57%, 38.6%, 74.28% and 77.14%, 74.28%, 80%, 57.14% and 80%, 80%, 82% respectively. The majority of patients with acute respiratory failure treated with BiPAP showed ABG parameters such as pH(<7.35), SaO2(94-100%), pO2(80-100mmHg), pCO2(35-45mmHg), and HCO3(22-26mEq/L) on admission, after an hour, 8 hours and 24 hours of admission, were 40%, 57.14%, 57.14%, 60% (Acidosis) and 68.5%, 62.85%, 57.14%, 60.7% and 74.28%, 62.85%, 57.14%, 51.42% and 60%, 57.14%, 51.42%, 60% and 77.14%, 77.14%, 74.28%, 85.71% respectively. Thus, the results showed that the respiratory parameter of the patients of HFNC was better with M=11.6, SD=1.35 when compared to the patients on BIPAP with M=13.51, SD =1.77 and an independent ‘t’ test was 5.232 at p<0.001. Hence, the null hypothesis stated that there was no difference in the respiratory parameters of patients on BIPAP and HFNC was rejected. This shows that HFNC was a better mode of ventilation.

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高流量鼻吸氧与无创通气对急性呼吸衰竭患者呼吸参数的影响

背景:护士在确保患者成功治疗方面发挥着关键作用。防止缺氧引起的细胞损伤，防止高碳酸血症引起的酸中毒，缓解患者的症状和痛苦，都需要充足的氧气水平。氧疗的目的是补充吸入氧浓度，以防止组织缺氧和随后的细胞功能障碍。细胞氧输送是一种依赖于吸入氧、血红蛋白浓度、其饱和氧能力和心输出量将氧输送到细胞的机制(Higgins, 2007)2。目的:比较高流量鼻吸氧与无创通气对急性呼吸衰竭患者呼吸参数的影响。方法:本研究采用描述性研究设计，仅采用前测后测设计。结果:大多数经HFNC治疗的急性呼吸衰竭患者入院时、入院后1 h、8 h、24 h的ABG参数pH(7.35 ~ 7.45)、SaO2(94 ~ 100%)、pO2(80 ~ 100mmhg)、pCO2(35 ~ 45mmhg)、HCO3(22 ~ 26meq /L)分别为62.85%、68.57%、68.6%、74.28%、67.14%、51.4%、47.71%、62.85%、68.57%、38.6%、74.28%、77.14%、74.28%、80%、57.14%、80%、82%。大多数接受BiPAP治疗的急性呼吸衰竭患者入院时、入院后1小时、8小时和24小时的ABG参数pH(<7.35)、SaO2(94-100%)、pO2(80-100mmHg)、pCO2(35-45mmHg)、HCO3(22-26mEq/L)分别为40%、57.14%、57.14%、60%(酸中毒)和68.5%、62.85%、57.14%、60.7%和74.28%、62.85%、57.14%、51.42%和60%、57.14%、51.42%、60%和77.14%、77.14%、74.28%、85.71%。由此可见，HFNC患者的呼吸参数(M=11.6, SD=1.35)优于BIPAP患者(M=13.51, SD= 1.77)，独立t检验为5.232,p<0.001。因此，否定BIPAP与HFNC患者呼吸参数无差异的原假设。这说明HFNC是一种较好的通气方式。

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Asian journal of nursing education and research

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