RESEARCH OF ANTIBACTERIAL PROPERTIES OF THE SURFACE OF THE TITANIUM ALLOYS VT5-1 AND VT6 CONVERTED TO ANATASE TO PREVENT BACTERIAL ADHESION

Abstract

Aim: to evaluate the effectiveness of preventing the formation of microbial biofilms on the surfaces of implants made of titanium alloys VT5-1, VT6 with a transformed surface into anatase. Materials and methods. The study was carried out in the bacteriological laboratory of the Severodonetsk multidisciplinary city hospital from January 2019 to September 2019. The ability to prevent the formation of microbial biofilms of Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa was evaluated. The static cell adhesion method and the disco diffuse method were used. The surface of the plates was examined on a XS 6220 UCMJS05100KPA microscope. The intensity of the formation of microbial biofilms on the plates was evaluated visually by the four-cross system. Results. On all coatings with anatase, in comparison with unmodified plates, the intensity of initial adhesion and the number of bacteria fixed on the surface of the colonies markedly decreased. On surfaces with silica crystals, biofilm formation was minimal. The altered surface of titanium alloys VT5-1 and VT6 anatase and anatase with silicon dioxide crystals does not inhibit microflora growth. Conclusions. The transformed surface of titanium implants into anatase and anatase with silicon dioxide crystals prevents the fixation of biofilms of microbial associations.