Dry Eye Changes After Phacoemulsification After Using Oral Linoleinic Acid (Omega 3 Fatty Acids)

Abd Elrahman Abd Elaleem, D. Ahmed, Mohamed Yasser Sayed Saif
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Abstract

: The current study was designed to evaluate the effect of oral linoleinec acid (omega 3 fatty acid) on patients who complained from dryness after Phacoemulsification. It was a Cross-Sectional study conducted first of April 2020 to end of February 2021 in the ophthalmology department at Beni-Suef University Hospital, and included 107 participants that had Phacoemulsification surgery, (60.7% males and 39.3% females), their age ranged from (48) to (71) with an average age of (62.07 ±6.03) years old. All participants were subjected to full clinical and laboratory investigations and received oral linoleinic acid capsules 1000 mg for 3 months after operation. Dry-eye markers including the ocular surface disease index (OSDI) and subjective symptom questionnaire, tear-film assessment using Schirmer testing 2, and break–up time test was sequentially evaluated preoperatively and postoperatively at 1st day,1st week, 1st month, 2nd month and 3rd month .Written Informed consent had been taken from all studied participants prior to beginning of the study. OSDI scores decreased significantly between baseline and three months post-operatively, YBUT scores increased significantly between baseline and three months post-operatively and Schirmer test scores increased significantly between baseline and three months post-operatively. Based on our results, oral omega-3 supplements could be safely added to the postoperative protocols following phacoemulsification to reduce the incidence of postoperative dry eye syndrome.
口服亚油酸(欧米伽- 3脂肪酸)对超声乳化术后干眼的影响
本研究旨在评估口服亚油酸(omega - 3脂肪酸)对超声乳化术后抱怨皮肤干燥的患者的影响。本研究于2020年4月1日至2021年2月底在贝尼-苏夫大学医院眼科进行横断面研究,纳入了107名接受超声乳化手术的参与者,其中男性占60.7%,女性占39.3%,年龄从48岁到71岁,平均年龄(62.07±6.03)岁。所有参与者都接受了全面的临床和实验室调查,并在手术后3个月口服亚油酸胶囊1000毫克。在术前和术后第1天、第1周、第1个月、第2个月和第3个月依次评估干眼指标,包括眼表疾病指数(OSDI)和主观症状问卷,使用Schirmer试验2进行泪膜评估和破裂时间测试。所有研究参与者在研究开始前均获得书面知情同意书。OSDI评分在基线和术后3个月间显著降低,YBUT评分在基线和术后3个月间显著升高,Schirmer测试评分在基线和术后3个月间显著升高。根据我们的研究结果,口服omega-3补充剂可以安全地添加到超声乳化术后的手术方案中,以减少术后干眼综合征的发生率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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