Effect of Mycotoxins on the Ultrastructure of Cortical Elements in Pig Nephrons

Abstract

reports the results of an electron microscopic study of pathomorphological changes in the kidneys of pigs exposed to the combined intoxication with fusariotoxins (T-2 toxin, deoxynivalenol, and zearalenone). Mycotoxicosis-related cytological changes of the glomeruli and proximal convoluted tubules were analyzed. A series of ultrastructural changes that occurred in the cellular elements involved in ultrafiltration and reabsorption were observed and ascribed to the development of nephropathy under chronic mycotoxication.