Chronic viral hepatitis and inflammatory bowel disease

Q3 Medicine

Voprosy Detskoi Dietologii Pub Date : 2021-12-25 DOI:10.20953/2224-5448-2021-2-29-34

G. Volynets, A. Khavkin

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引用次数: 0

Abstract

The article presents the results of a literature review devoted to the study of the problems of the combined course of inflammatory bowel diseases (IBD), which include ulcerative colitis (UC) and Crohn's disease (CD), and chronic viral hepatitis (CVH) – chronic hepatitis B (CHB) and chronic hepatitis C (CHC). The frequency of occurrence of CHB and CHC in IBD in different countries is presented, which ranges from 1 to 9%. The clinical course of these combined diseases, the possibility of reactivation of hepatitis B virus (HBV) and hepatitis C virus (HCV) during immunosuppressive therapy are described. Recommendations on the specifics of examination and management of patients with combined pathology of IBD and CVH are presented. Conclusion. The combined pathology of IBD and CVH is a significant public health problem around the world that requires further large-scale study. The use of immunosuppressive therapy for IBD can be accompanied by the activation of HBV and HCV infection, therefore, the management of such patients should be individualized. Key words: inflammatory bowel disease, chronic hepatitis B, chronic hepatitis C, immunosuppressive therapy

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慢性病毒性肝炎和炎症性肠病

本文介绍了一篇致力于研究炎症性肠病(IBD)联合病程问题的文献综述的结果，其中包括溃疡性结肠炎(UC)和克罗恩病(CD)，以及慢性病毒性肝炎(CVH) -慢性乙型肝炎(CHB)和慢性丙型肝炎(CHC)。介绍了不同国家IBD中CHB和CHC的发生频率，其范围为1%至9%。本文描述了这些合并疾病的临床过程，以及免疫抑制治疗期间乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)再激活的可能性。提出了关于IBD和CVH合并病理患者的具体检查和管理的建议。结论。IBD和CVH的联合病理是世界范围内的一个重大公共卫生问题，需要进一步的大规模研究。使用免疫抑制治疗IBD可能伴随着HBV和HCV感染的激活，因此，这类患者的管理应个体化。关键词:炎症性肠病，慢性乙型肝炎，慢性丙型肝炎，免疫抑制治疗

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Voprosy Detskoi Dietologii Medicine-Pediatrics, Perinatology and Child Health

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： The scientific journal Voprosy Detskoi Dietologii is included in the Scopus database. Publisher country is RU. The main subject areas of published articles are Food Science, Pediatrics, Perinatology, and Child Health, Nutrition and Dietetics, Клиническая медицина.