Treatment of complex urethral stenosis in public centers from developing countries in 21st century

S. Tucci Jr., Henrique Florindo
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引用次数: 1

Abstract

Access to surgical treatment may be the only solution for preventing chronic disabilities and mortality (1) in cases of traumatic injuries and countless other situations that significantly affect quality of life such as iatrogenic, inflammatory or neoplastic injury. Notwithstanding successful prevention strategies, these conditions are responsible for a significant portion of disease burden in the population. In practice, speedy access to essential surgery is not always widely guaranteed (2), although it is part of the human right to health. In developing countries, where the most appropriate treatment for various diseases is not always readily available (2), there is a high incidence of complications from delays in diagnosis or access to specialized centers. In Brazil, this is the context in which complex urethral stenosis in public university institutions linked to the Unified Health System is approached. Male urethral stenosis has significant negative impact on patients’ quality of life. Its pathophysiology is better known and differences between developed and developing countries must be considered. The recent study by Astolfi et al, (3) evaluating 899 patients, shows that in Brazil iatrogenesis was the most frequent cause (43.2%), followed by idiopathic (21.7%) and traumatic (21.5%). Of the inflammatory causes (13.7%), the largest part was due to scleroatrophic lichen (66.7%), and 33.4% to infectious urethritis. Regarding the stenosis site, Palminteri et al. (4) showed that in developed countries, stenosis occurs mainly in the anterior urethra (92.2%), particularly in the bulbar segment (45.9%), with involvement of the posterior urethra in only 7.8% of cases (5). Most trauma-related stenosis occurred in urethral lesions associated with pelvic fractures (62.7%) and 62.7% were associated with perineal trauma. Of iatrogenic causes, 59% were secondary to urethral instrumentation (catheterization and other procedures), 24.8% due to procedures such as prostatectomy, radiotherapy and postectomy, and 16.2% following failure to correct hypospadias. Such demographic data are useful in guiding the development of preventive and therapeutic population strategies, as well as being important for educational guidance in relation to manipulation of the urethra (6), from vesicoureteral catheterization to instrumentation of the urethra in therapeutic procedures and, above all, to learn the different urethroplasty techniques. Strategies must be guided by the Unified Health System (SUS) as set forth in Article 5 of Law 8.080 of September 1990, and educational guidance is an obligation of medical schools and specific courses in Urology as a specialty. The SUS offers universal coverage and free access to all levels of health care for each person Treatment of complex urethral stenosis in public centers from developing countries in 21st century _______________________________________________
21世纪发展中国家公共中心复杂性尿道狭窄的治疗
在创伤性损伤和无数其他严重影响生活质量的情况下,如医源性、炎症性或肿瘤性损伤,获得手术治疗可能是预防慢性残疾和死亡的唯一解决方案。尽管采取了成功的预防战略,但这些疾病造成了人口中很大一部分疾病负担。在实践中,迅速获得基本手术并不总是得到广泛保证(2),尽管这是健康权的一部分。在发展中国家,各种疾病的最适当治疗方法并不总是现成的(2),由于诊断延误或无法进入专门中心,并发症的发生率很高。在巴西,这是与统一卫生系统相关的公立大学机构复杂尿道狭窄的背景。男性尿道狭窄对患者生活质量有显著的负面影响。它的病理生理学更为人所知,必须考虑到发达国家和发展中国家之间的差异。Astolfi等人(3)最近对899例患者进行的研究显示,在巴西,医源性是最常见的原因(43.2%),其次是特发性(21.7%)和外伤性(21.5%)。在炎症原因中,以硬萎缩性地衣(66.7%)为主(13.7%),感染性尿道炎占33.4%。关于狭窄部位,Palminteri等(4)研究表明,在发达国家,狭窄主要发生在前尿道(92.2%),尤其是球段(45.9%),累及后尿道的病例仅占7.8%(5)。创伤性狭窄多发生在骨盆骨折相关的尿道病变中(62.7%),62.7%与会阴创伤相关。医源性原因中,59%继发于尿道内固定(置管和其他手术),24.8%继发于前列腺切除术、放疗和术后手术,16.2%继发于尿道下裂矫正失败。这样的人口统计数据对于指导预防和治疗人群策略的发展是有用的,同时对于尿道操作的教育指导也是重要的(6),从膀胱输尿管导尿到治疗过程中的尿道器械,最重要的是,学习不同的尿道成形术技术。战略必须以1990年9月第8.080号法律第5条规定的统一卫生系统(SUS)为指导,教育指导是医学院和泌尿外科专业特定课程的义务。统一卫生系统为每个人提供普遍覆盖和免费获得各级卫生保健的机会,在21世纪发展中国家的公共中心治疗复杂尿道狭窄_______________________________________________
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