Chemical constituents of two Ecuadorian medicinal plants, Tagetes terniflora Kunth and Croton rivinifolius Kunth

A. Suárez, Vladimir Morocho, Vladimir Luna, Katty Castillo, Chabaco Armijos
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Abstract

Phytochemical study of two medicinal plants from Ecuador, Tagetes terniflora Kunth, and Croton rivinifolius Kunth, led to the isolation and characterization of the major constituents present in the organic extracts obtained from these plants: 5-(4-acetoxy-1-butynil)-2,2’-bi-thiophene (1), 5-methyl-2,2’:5’,2”- terthiophene (2), patuletin (3) from Tagetes terniflora, and isocorydine (4), sweroside (5), tiliroside (6) from Croton rivinifolius. The structures of these compounds were established by spectroscopic analysis including two-dimensional NMR methods, MS, and comparison with published spectral data. They are recognized as secondary metabolites that represent the chemotaxonomy of Tagetes and Croton genera and could be responsible for the recognized medicinal properties attributed to these species. This paper deals with the first report that shows the presence of these compounds in these plants.
两种厄瓜多尔药用植物万寿菊(Tagetes terniflora Kunth)和Croton rivinifolius Kunth的化学成分
对厄瓜多尔两种药用植物万寿菊(Tagetes terniflora Kunth)和克罗通(Croton riviniolius Kunth)进行了植物化学研究,分离并鉴定了从这些植物中获得的有机提取物中的主要成分:5 -(4-乙酰氧基-1-丁基)-2,2 ' -双噻吩(1),5-甲基-2,2 ':5 ',2 " -噻吩(2),从万寿菊(Tagetes terniflora)中提取的球柳素(3),从克罗通(Croton riviniolius)中提取的异堇苷(4),草苷(5),铁苷(6)。这些化合物的结构通过波谱分析,包括二维核磁共振方法,质谱,并与已发表的光谱数据进行比较。它们被认为是次生代谢物,代表了万寿菊和豌豆属的化学分类,可能是这些物种公认的药用特性的原因。本文报道了首次在这些植物中发现这些化合物的报道。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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