Characteristics of a new variant of rabbit haemorrhagic disease virus – RHDV2

Q3 Biochemistry, Genetics and Molecular Biology
Dominika Bębnowska, P. Niedźwiedzka-Rystwej
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引用次数: 10

Abstract

RHD (Rabbit Haemorrhagic Disease) is an etiologic agent that causes viral haemorrhagic disease of rabbits, which is also referred to as rabbit plague. The desire to explore knowledge about this pathogen in the world results not only from its similarity to human hemorrhagic fevers, for which RHDV can be considered as a good research model. It is also important that with myxomatosis, rabbit plague is the most severe viral disease of these animals. Describing the classic RHDV virus, followed by RHDVa, which is considered the first described antigenic variant of the RHD virus, allowed to become familiar with the information that until now constituted the basic building block of the control of viral haemorrhagic disease of rabbits in the world. However, the attributes of RHDV2, characterized only in 2010, differ significantly from the specifics of RHDV strains known to date. What’s more, the global expansion of this pathogen has significantly changed the RHD image, the methods of its identification, control and eradication. The completely changed face of the virus that causes rabbit plague causes that the belief about full supervision over RHD is now obsolete.
兔出血性疾病病毒新变种RHDV2的特征
兔出血性疾病(RHD)是引起兔病毒性出血性疾病的病原,也被称为兔鼠疫。人们渴望在世界范围内探索关于这种病原体的知识,不仅是因为它与人类出血热相似,因此RHDV可以被认为是一种很好的研究模型。同样重要的是,与粘液瘤病一起,兔鼠疫是这些动物中最严重的病毒性疾病。描述了经典的RHDV病毒,随后描述了RHDVa, RHDVa被认为是RHD病毒的第一个被描述的抗原变体,使我们熟悉了迄今为止构成世界上兔子病毒性出血性疾病控制的基本组成部分的信息。然而,仅在2010年发现的RHDV2的特性与迄今已知的rhdvv毒株的特性有很大不同。此外,该病原体在全球范围内的扩展显著改变了RHD的形象、鉴定、控制和根除方法。导致兔鼠疫的病毒完全改变了面貌,这使得对RHD进行全面监管的信念现在已经过时了。
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来源期刊
Acta Biologica Hungarica
Acta Biologica Hungarica 生物-生物学
CiteScore
1.40
自引率
0.00%
发文量
0
审稿时长
3 months
期刊介绍: Acta Biologica Hungarica provides a forum for original research works in the field of experimental biology. It covers cytology, functional morphology, embriology, genetics, endocrinology, cellular physiology, plant physiology, neurobiology, ethology and environmental biology with emphasis on toxicology. Publishes book reviews and advertisements.
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